Bosma PJ - Search Results

1

Gene replacement therapy for genetic hepatocellular jaundice.

van Dijk R, Beuers U, Bosma PJ. van Dijk R, et al. Among authors: bosma pj. Clin Rev Allergy Immunol. 2015 Jun;48(2-3):243-53. doi: 10.1007/s12016-014-8454-7. Clin Rev Allergy Immunol. 2015. PMID: 25315738 Review.

2

Sequence of exons and the flanking regions of human bilirubin-UDP-glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler-Najjar syndrome, type I.

Bosma PJ, Chowdhury NR, Goldhoorn BG, Hofker MH, Oude Elferink RP, Jansen PL, Chowdhury JR. Bosma PJ, et al. Hepatology. 1992 May;15(5):941-7. doi: 10.1002/hep.1840150531. Hepatology. 1992. PMID: 1568736

3

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.

Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, Lindhout D, Tytgat GN, Jansen PL, Oude Elferink RP, et al. Bosma PJ, et al. N Engl J Med. 1995 Nov 2;333(18):1171-5. doi: 10.1056/NEJM199511023331802. N Engl J Med. 1995. PMID: 7565971 Free article.

4

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene.

Paulusma CC, Bosma PJ, Zaman GJ, Bakker CT, Otter M, Scheffer GL, Scheper RJ, Borst P, Oude Elferink RP. Paulusma CC, et al. Among authors: bosma pj. Science. 1996 Feb 23;271(5252):1126-8. doi: 10.1126/science.271.5252.1126. Science. 1996. PMID: 8599091

5

The current state of cancer gene therapy and its application in esophageal carcinoma.

Buskens CJ, Marsman WA, Bosma PJ, van Lanschot JJ. Buskens CJ, et al. Among authors: bosma pj. Dig Surg. 2005;22(4):222-33. doi: 10.1159/000088052. Epub 2005 Sep 20. Dig Surg. 2005. PMID: 16174979 Review.

6

Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats.

Seppen J, Bakker C, de Jong B, Kunne C, van den Oever K, Vandenberghe K, de Waart R, Twisk J, Bosma P. Seppen J, et al. Mol Ther. 2006 Jun;13(6):1085-92. doi: 10.1016/j.ymthe.2006.01.014. Epub 2006 Apr 3. Mol Ther. 2006. PMID: 16581301 Free article.

7

Towards liver-directed gene therapy for Crigler-Najjar syndrome.

Miranda PS, Bosma PJ. Miranda PS, et al. Among authors: bosma pj. Curr Gene Ther. 2009 Apr;9(2):72-82. doi: 10.2174/156652309787909508. Curr Gene Ther. 2009. PMID: 19355865 Review.

8

Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

Montenegro-Miranda PS, Sneitz N, de Waart DR, Ten Bloemendaal L, Duijst S, de Knegt RJ, Beuers U, Finel M, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: bosma pj. Biochim Biophys Acta. 2012 Aug;1822(8):1223-9. doi: 10.1016/j.bbadis.2012.04.013. Epub 2012 Apr 21. Biochim Biophys Acta. 2012. PMID: 22546842 Free article.

9

Polyinosinic acid blocks adeno-associated virus macrophage endocytosis in vitro and enhances adeno-associated virus liver-directed gene therapy in vivo.

van Dijk R, Montenegro-Miranda PS, Riviere C, Schilderink R, ten Bloemendaal L, van Gorp J, Duijst S, de Waart DR, Beuers U, Haisma HJ, Bosma PJ. van Dijk R, et al. Among authors: bosma pj. Hum Gene Ther. 2013 Sep;24(9):807-13. doi: 10.1089/hum.2013.086. Hum Gene Ther. 2013. PMID: 24010701

10

In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV.

Montenegro-Miranda PS, Pichard V, Aubert D, Ten Bloemendaal L, Duijst S, de Waart DR, Ferry N, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: bosma pj. Gene Ther. 2014 Feb;21(2):168-74. doi: 10.1038/gt.2013.69. Epub 2013 Nov 28. Gene Ther. 2014. PMID: 24285217

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