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Therapeutic HPV Cancer Vaccine Targeted to CD40 Elicits Effective CD8+ T-cell Immunity.
Yin W, Duluc D, Joo H, Xue Y, Gu C, Wang Z, Wang L, Ouedraogo R, Oxford L, Clark A, Parikh F, Kim-Schulze S, Thompson-Snipes L, Lee SY, Beauregard C, Woo JH, Zurawski S, Sikora AG, Zurawski G, Oh S. Yin W, et al. Among authors: parikh f. Cancer Immunol Res. 2016 Oct;4(10):823-834. doi: 10.1158/2326-6066.CIR-16-0128. Epub 2016 Aug 2. Cancer Immunol Res. 2016. PMID: 27485136
Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2.
Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Lopez-Rivera E, et al. Among authors: parikh f. Cancer Res. 2014 Feb 15;74(4):1067-78. doi: 10.1158/0008-5472.CAN-13-0588. Epub 2014 Jan 7. Cancer Res. 2014. PMID: 24398473 Free PMC article.
Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy.
Hanoteau A, Newton JM, Krupar R, Huang C, Liu HC, Gaspero A, Gartrell RD, Saenger YM, Hart TD, Santegoets SJ, Laoui D, Spanos C, Parikh F, Jayaraman P, Zhang B, Van der Burg SH, Van Ginderachter JA, Melief CJM, Sikora AG. Hanoteau A, et al. Among authors: parikh f. J Immunother Cancer. 2019 Jan 15;7(1):10. doi: 10.1186/s40425-018-0485-9. J Immunother Cancer. 2019. PMID: 30646957 Free PMC article.
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release.
Jayaraman P, Parikh F, Lopez-Rivera E, Hailemichael Y, Clark A, Ma G, Cannan D, Ramacher M, Kato M, Overwijk WW, Chen SH, Umansky VY, Sikora AG. Jayaraman P, et al. Among authors: parikh f. J Immunol. 2012 Jun 1;188(11):5365-76. doi: 10.4049/jimmunol.1103553. Epub 2012 Apr 23. J Immunol. 2012. PMID: 22529296 Free PMC article.
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.
Newton JM, Hanoteau A, Liu HC, Gaspero A, Parikh F, Gartrell-Corrado RD, Hart TD, Laoui D, Van Ginderachter JA, Dharmaraj N, Spanos WC, Saenger Y, Young S, Sikora AG. Newton JM, et al. Among authors: parikh f. J Immunother Cancer. 2019 Aug 13;7(1):216. doi: 10.1186/s40425-019-0698-6. J Immunother Cancer. 2019. PMID: 31409394 Free PMC article. Clinical Trial.
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.
Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG. Jayaraman P, et al. Among authors: parikh f. Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018. Oncoimmunology. 2018. PMID: 30288358 Free PMC article.
241 results