Hart MH - Search Results

1

Functional analysis of the anti-adalimumab response using patient-derived monoclonal antibodies.

van Schouwenburg PA, Kruithof S, Votsmeier C, van Schie K, Hart MH, de Jong RN, van Buren EE, van Ham M, Aarden L, Wolbink G, Wouters D, Rispens T. van Schouwenburg PA, et al. Among authors: hart mh. J Biol Chem. 2014 Dec 12;289(50):34482-8. doi: 10.1074/jbc.M114.615500. Epub 2014 Oct 17. J Biol Chem. 2014. PMID: 25326381 Free PMC article. Review.

2

Variable mannose-binding lectin expression during postoperative acute-phase response.

Van Till JW, Boermeester MA, Modderman PW, Van Sandick JW, Hart MH, Gisbertz SS, Van Lanschot JJ, Aarden LA. Van Till JW, et al. Among authors: hart mh. Surg Infect (Larchmt). 2006 Oct;7(5):443-52. doi: 10.1089/sur.2006.7.443. Surg Infect (Larchmt). 2006. PMID: 17083310

3

A novel method for the detection of antibodies to adalimumab in the presence of drug reveals "hidden" immunogenicity in rheumatoid arthritis patients.

van Schouwenburg PA, Bartelds GM, Hart MH, Aarden L, Wolbink GJ, Wouters D. van Schouwenburg PA, et al. Among authors: hart mh. J Immunol Methods. 2010 Oct 31;362(1-2):82-8. doi: 10.1016/j.jim.2010.09.005. Epub 2010 Sep 9. J Immunol Methods. 2010. PMID: 20833178

4

Surprising negative association between IgG1 allotype disparity and anti-adalimumab formation: a cohort study.

Bartelds GM, de Groot E, Nurmohamed MT, Hart MH, van Eede PH, Wijbrandts CA, Crusius JB, Dijkmans BA, Tak PP, Aarden L, Wolbink GJ. Bartelds GM, et al. Among authors: hart mh. Arthritis Res Ther. 2010;12(6):R221. doi: 10.1186/ar3208. Epub 2010 Dec 27. Arthritis Res Ther. 2010. PMID: 21187010 Free PMC article.

5

Differential effect of drug interference in immunogenicity assays.

Hart MH, de Vrieze H, Wouters D, Wolbink GJ, Killestein J, de Groot ER, Aarden LA, Rispens T. Hart MH, et al. J Immunol Methods. 2011 Sep 30;372(1-2):196-203. doi: 10.1016/j.jim.2011.07.019. Epub 2011 Jul 29. J Immunol Methods. 2011. PMID: 21824477

6

Patients non-responding to etanercept obtain lower etanercept concentrations compared with responding patients.

Jamnitski A, Krieckaert CL, Nurmohamed MT, Hart MH, Dijkmans BA, Aarden L, Voskuyl AE, Wolbink GJ. Jamnitski A, et al. Among authors: hart mh. Ann Rheum Dis. 2012 Jan;71(1):88-91. doi: 10.1136/annrheumdis-2011-200184. Epub 2011 Sep 12. Ann Rheum Dis. 2012. PMID: 21914626 Clinical Trial.

7

The minipig as an alternative non-rodent model for immunogenicity testing using the TNFα blockers adalimumab and infliximab.

van Mierlo GJ, Cnubben NH, Wouters D, Wolbink GJ, Hart MH, Rispens T, Ganderup NC, Kuper CF, Aarden L, Penninks AH. van Mierlo GJ, et al. Among authors: hart mh. J Immunotoxicol. 2014 Jan-Mar;11(1):62-71. doi: 10.3109/1547691X.2013.796023. Epub 2013 Jun 5. J Immunotoxicol. 2014. PMID: 23738746 Free article.

8

Drug interference in immunogenicity assays depends on valency.

Rispens T, Hart MH, Ooijevaar-de Heer P, van Leeuwen A, Vennegoor A, Killestein J, Wolbink GJ, van der Kleij D. Rispens T, et al. Among authors: hart mh. J Pharm Biomed Anal. 2013 Nov;85:179-85. doi: 10.1016/j.jpba.2013.07.022. Epub 2013 Jul 30. J Pharm Biomed Anal. 2013. PMID: 23954437

9

The antibody response against human and chimeric anti-TNF therapeutic antibodies primarily targets the TNF binding region.

van Schie KA, Hart MH, de Groot ER, Kruithof S, Aarden LA, Wolbink GJ, Rispens T. van Schie KA, et al. Among authors: hart mh. Ann Rheum Dis. 2015 Jan;74(1):311-4. doi: 10.1136/annrheumdis-2014-206237. Epub 2014 Oct 23. Ann Rheum Dis. 2015. PMID: 25342759

10

TFPI inhibits lectin pathway of complement activation by direct interaction with MASP-2.

Keizer MP, Pouw RB, Kamp AM, Patiwael S, Marsman G, Hart MH, Zeerleder S, Kuijpers TW, Wouters D. Keizer MP, et al. Among authors: hart mh. Eur J Immunol. 2015 Feb;45(2):544-50. doi: 10.1002/eji.201445070. Epub 2014 Nov 27. Eur J Immunol. 2015. PMID: 25359215 Free article.

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