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Plasma membrane phospholipase A2 controls hepatocellular fatty acid uptake and is responsive to pharmacological modulation: implications for nonalcoholic steatohepatitis.
Stremmel W, Staffer S, Wannhoff A, Pathil A, Chamulitrat W. Stremmel W, et al. Among authors: wannhoff a. FASEB J. 2014 Jul;28(7):3159-70. doi: 10.1096/fj.14-249763. Epub 2014 Apr 9. FASEB J. 2014. PMID: 24719358
Moreover, steatosis and inflammation were abrogated by UDCA-LPE treatment in a cellular model of NASH. Thus, iPLA2beta acts as an upstream checkpoint for mechanisms that regulate fatty acid uptake, and its inhibition by UDCA-LPE qualifies this nontoxic compound as a
Moreover, steatosis and inflammation were abrogated by UDCA-LPE treatment in a cellular model of NASH. Thus, iPLA2beta acts as an ups …
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival.
Friedrich K, Wannhoff A, Kattner S, Brune M, Hov JR, Weiss KH, Antoni C, Dollinger M, Neumann-Haefelin C, Seufferlein T, Schemmer P, Schirmacher P, Stremmel W, Gotthardt DN. Friedrich K, et al. Among authors: wannhoff a. J Gastroenterol Hepatol. 2014;29(7):1477-84. doi: 10.1111/jgh.12540. J Gastroenterol Hepatol. 2014. PMID: 25273282
Reduction in alkaline phosphatase is associated with longer survival in primary sclerosing cholangitis, independent of dominant stenosis.
Rupp C, Rössler A, Halibasic E, Sauer P, Weiss KH, Friedrich K, Wannhoff A, Stiehl A, Stremmel W, Trauner M, Gotthardt DN. Rupp C, et al. Among authors: wannhoff a. Aliment Pharmacol Ther. 2014 Dec;40(11-12):1292-301. doi: 10.1111/apt.12979. Epub 2014 Oct 14. Aliment Pharmacol Ther. 2014. PMID: 25316001 Free article.
63 results