A mutation in the canalicular phospholipid transporter gene, ABCB4, is associated with cholestasis, ductopenia, and cirrhosis in adults.
Gotthardt D, Runz H, Keitel V, Fischer C, Flechtenmacher C, Wirtenberger M, Weiss KH, Imparato S, Braun A, Hemminki K, Stremmel W, Rüschendorf F, Stiehl A, Kubitz R, Burwinkel B, Schirmacher P, Knisely AS, Zschocke J, Sauer P.
Gotthardt D, et al. Among authors: weiss kh.
Hepatology. 2008 Oct;48(4):1157-66. doi: 10.1002/hep.22485.
Hepatology. 2008.
PMID: 18781607