Dorai H - Search Results

1

The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups.

Cooper PR, Kliwinski CM, Perkinson RA, Ragwan E, Mabus JR, Powers GD, Dorai H, Giles-Komar J, Hornby PJ. Cooper PR, et al. Among authors: dorai h. Front Pharmacol. 2014 Oct 7;5:225. doi: 10.3389/fphar.2014.00225. eCollection 2014. Front Pharmacol. 2014. PMID: 25339905 Free PMC article.

2

Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis.

Hornby PJ, Cooper PR, Kliwinski C, Ragwan E, Mabus JR, Harman B, Thompson S, Kauffman AL, Yan Z, Tam SH, Dorai H, Powers GD, Giles-Komar J. Hornby PJ, et al. Among authors: dorai h. Pharm Res. 2014 Apr;31(4):908-22. doi: 10.1007/s11095-013-1212-3. Epub 2013 Sep 26. Pharm Res. 2014. PMID: 24072267 Free PMC article.

3

The impact of anti-apoptotic gene Bcl-2∆ expression on CHO central metabolism.

Templeton N, Lewis A, Dorai H, Qian EA, Campbell MP, Smith KD, Lang SE, Betenbaugh MJ, Young JD. Templeton N, et al. Among authors: dorai h. Metab Eng. 2014 Sep;25:92-102. doi: 10.1016/j.ymben.2014.06.010. Epub 2014 Jul 8. Metab Eng. 2014. PMID: 25014175

4

Correlation of heavy and light chain mRNA copy numbers to antibody productivity in mouse myeloma production cell lines.

Dorai H, Csirke B, Scallon B, Ganguly S. Dorai H, et al. Hybridoma (Larchmt). 2006 Feb;25(1):1-9. doi: 10.1089/hyb.2006.25.1. Hybridoma (Larchmt). 2006. PMID: 16475875

5

Expression of anti-apoptosis genes alters lactate metabolism of Chinese Hamster Ovary cells in culture.

Dorai H, Kyung YS, Ellis D, Kinney C, Lin C, Jan D, Moore G, Betenbaugh MJ. Dorai H, et al. Biotechnol Bioeng. 2009 Jun 15;103(3):592-608. doi: 10.1002/bit.22269. Biotechnol Bioeng. 2009. PMID: 19241388

6

Development of mammalian production cell lines expressing CNTO736, a glucagon like peptide-1-MIMETIBODY: factors that influence productivity and product quality.

Dorai H, Nemeth JF, Cammaart E, Wang Y, Tang QM, Magill A, Lewis MJ, Raju TS, Picha K, O'Neil K, Ganguly S, Moore G. Dorai H, et al. Biotechnol Bioeng. 2009 May 1;103(1):162-76. doi: 10.1002/bit.22217. Biotechnol Bioeng. 2009. PMID: 19137588

7

Genome-wide analysis of mouse myeloma cell lines expressing therapeutic antibodies.

Dorai H, Li K, Huang CC, Bittner A, Galindo J, Carmen A. Dorai H, et al. Biotechnol Prog. 2007 Jul-Aug;23(4):911-20. doi: 10.1021/bp0700051. Epub 2007 Jun 26. Biotechnol Prog. 2007. PMID: 17592857

8

Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.

Dorai H, Corisdeo S, Ellis D, Kinney C, Chomo M, Hawley-Nelson P, Moore G, Betenbaugh MJ, Ganguly S. Dorai H, et al. Biotechnol Bioeng. 2012 Apr;109(4):1016-30. doi: 10.1002/bit.24367. Epub 2011 Dec 1. Biotechnol Bioeng. 2012. PMID: 22068683

9

Mammalian cell-produced therapeutic proteins: heterogeneity derived from protein degradation.

Dorai H, Ganguly S. Dorai H, et al. Curr Opin Biotechnol. 2014 Dec;30:198-204. doi: 10.1016/j.copbio.2014.07.007. Epub 2014 Aug 12. Curr Opin Biotechnol. 2014. PMID: 25118137 Review.

10

Application of ¹³C flux analysis to identify high-productivity CHO metabolic phenotypes.

Templeton N, Smith KD, McAtee-Pereira AG, Dorai H, Betenbaugh MJ, Lang SE, Young JD. Templeton N, et al. Among authors: dorai h. Metab Eng. 2017 Sep;43(Pt B):218-225. doi: 10.1016/j.ymben.2017.01.008. Epub 2017 Jan 23. Metab Eng. 2017. PMID: 28122259

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