Lei QY - Search Results

1

NOTCH-induced aldehyde dehydrogenase 1A1 deacetylation promotes breast cancer stem cells.

Zhao D, Mo Y, Li MT, Zou SW, Cheng ZL, Sun YP, Xiong Y, Guan KL, Lei QY. Zhao D, et al. Among authors: lei qy. J Clin Invest. 2014 Dec;124(12):5453-65. doi: 10.1172/JCI76611. Epub 2014 Nov 10. J Clin Invest. 2014. PMID: 25384215 Free PMC article. Clinical Trial.

2

Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer.

Zhao D, Zou SW, Liu Y, Zhou X, Mo Y, Wang P, Xu YH, Dong B, Xiong Y, Lei QY, Guan KL. Zhao D, et al. Among authors: lei qy. Cancer Cell. 2013 Apr 15;23(4):464-76. doi: 10.1016/j.ccr.2013.02.005. Epub 2013 Mar 21. Cancer Cell. 2013. PMID: 23523103 Free PMC article.

3

Estrogen regulates Hippo signaling via GPER in breast cancer.

Zhou X, Wang S, Wang Z, Feng X, Liu P, Lv XB, Li F, Yu FX, Sun Y, Yuan H, Zhu H, Xiong Y, Lei QY, Guan KL. Zhou X, et al. Among authors: lei qy. J Clin Invest. 2015 May;125(5):2123-35. doi: 10.1172/JCI79573. Epub 2015 Apr 20. J Clin Invest. 2015. PMID: 25893606 Free PMC article.

4

Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

Lv L, Li D, Zhao D, Lin R, Chu Y, Zhang H, Zha Z, Liu Y, Li Z, Xu Y, Wang G, Huang Y, Xiong Y, Guan KL, Lei QY. Lv L, et al. Among authors: lei qy. Mol Cell. 2011 Jun 24;42(6):719-30. doi: 10.1016/j.molcel.2011.04.025. Mol Cell. 2011. PMID: 21700219 Free PMC article.

5

Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.

Lin R, Tao R, Gao X, Li T, Zhou X, Guan KL, Xiong Y, Lei QY. Lin R, et al. Among authors: lei qy. Mol Cell. 2013 Aug 22;51(4):506-518. doi: 10.1016/j.molcel.2013.07.002. Epub 2013 Aug 8. Mol Cell. 2013. PMID: 23932781 Free PMC article.

6

Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization.

Lv L, Xu YP, Zhao D, Li FL, Wang W, Sasaki N, Jiang Y, Zhou X, Li TT, Guan KL, Lei QY, Xiong Y. Lv L, et al. Among authors: lei qy. Mol Cell. 2013 Nov 7;52(3):340-52. doi: 10.1016/j.molcel.2013.09.004. Epub 2013 Oct 10. Mol Cell. 2013. PMID: 24120661 Free PMC article.

7

Glyceraldehyde-3-phosphate dehydrogenase is activated by lysine 254 acetylation in response to glucose signal.

Li T, Liu M, Feng X, Wang Z, Das I, Xu Y, Zhou X, Sun Y, Guan KL, Xiong Y, Lei QY. Li T, et al. Among authors: lei qy. J Biol Chem. 2014 Feb 7;289(6):3775-85. doi: 10.1074/jbc.M113.531640. Epub 2013 Dec 21. J Biol Chem. 2014. PMID: 24362262 Free PMC article.

8

Oxidative stress activates SIRT2 to deacetylate and stimulate phosphoglycerate mutase.

Xu Y, Li F, Lv L, Li T, Zhou X, Deng CX, Guan KL, Lei QY, Xiong Y. Xu Y, et al. Among authors: lei qy. Cancer Res. 2014 Jul 1;74(13):3630-42. doi: 10.1158/0008-5472.CAN-13-3615. Epub 2014 May 1. Cancer Res. 2014. PMID: 24786789 Free PMC article.

9

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS.

Chen Y, Zhang J, Lin Y, Lei Q, Guan KL, Zhao S, Xiong Y. Chen Y, et al. EMBO Rep. 2011 Jun;12(6):534-41. doi: 10.1038/embor.2011.65. Epub 2011 May 13. EMBO Rep. 2011. PMID: 21566644 Free PMC article.

10

The Hippo-YAP pathway: new connections between regulation of organ size and cancer.

Zhao B, Lei QY, Guan KL. Zhao B, et al. Among authors: lei qy. Curr Opin Cell Biol. 2008 Dec;20(6):638-46. doi: 10.1016/j.ceb.2008.10.001. Epub 2008 Nov 18. Curr Opin Cell Biol. 2008. PMID: 18955139 Free PMC article. Review.

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