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Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.
Yu W, McPherson JR, Stevenson M, van Eijk R, Heng HL, Newey P, Gan A, Ruano D, Huang D, Poon SL, Ong CK, van Wezel T, Cavaco B, Rozen SG, Tan P, Teh BT, Thakker RV, Morreau H. Yu W, et al. Among authors: teh bt. J Clin Endocrinol Metab. 2015 Feb;100(2):E360-4. doi: 10.1210/jc.2014-3238. Epub 2014 Nov 11. J Clin Endocrinol Metab. 2015. PMID: 25387265
Alternative genetic pathways in parathyroid tumorigenesis.
Farnebo F, Kytölä S, Teh BT, Dwight T, Wong FK, Höög A, Elvius M, Wassif WS, Thompson NW, Farnebo LO, Sandelin K, Larsson C. Farnebo F, et al. Among authors: teh bt. J Clin Endocrinol Metab. 1999 Oct;84(10):3775-80. doi: 10.1210/jcem.84.10.6057. J Clin Endocrinol Metab. 1999. PMID: 10523029
HRPT2, encoding parafibromin, is mutated in hyperparathyroidism-jaw tumor syndrome.
Carpten JD, Robbins CM, Villablanca A, Forsberg L, Presciuttini S, Bailey-Wilson J, Simonds WF, Gillanders EM, Kennedy AM, Chen JD, Agarwal SK, Sood R, Jones MP, Moses TY, Haven C, Petillo D, Leotlela PD, Harding B, Cameron D, Pannett AA, Höög A, Heath H 3rd, James-Newton LA, Robinson B, Zarbo RJ, Cavaco BM, Wassif W, Perrier ND, Rosen IB, Kristoffersson U, Turnpenny PD, Farnebo LO, Besser GM, Jackson CE, Morreau H, Trent JM, Thakker RV, Marx SJ, Teh BT, Larsson C, Hobbs MR. Carpten JD, et al. Among authors: teh bt. Nat Genet. 2002 Dec;32(4):676-80. doi: 10.1038/ng1048. Epub 2002 Nov 18. Nat Genet. 2002. PMID: 12434154
HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours.
Howell VM, Haven CJ, Kahnoski K, Khoo SK, Petillo D, Chen J, Fleuren GJ, Robinson BG, Delbridge LW, Philips J, Nelson AE, Krause U, Hammje K, Dralle H, Hoang-Vu C, Gimm O, Marsh DJ, Morreau H, Teh BT. Howell VM, et al. Among authors: teh bt. J Med Genet. 2003 Sep;40(9):657-63. doi: 10.1136/jmg.40.9.657. J Med Genet. 2003. PMID: 12960210 Free PMC article.
HRPT2 and parathyroid cancer.
Marsh DJ, Morreau H, Teh BT. Marsh DJ, et al. Among authors: teh bt. Lancet Oncol. 2004 Feb;5(2):78. doi: 10.1016/S1470-2045(04)01379-8. Lancet Oncol. 2004. PMID: 14761810 No abstract available.
Gene expression of parathyroid tumors: molecular subclassification and identification of the potential malignant phenotype.
Haven CJ, Howell VM, Eilers PH, Dunne R, Takahashi M, van Puijenbroek M, Furge K, Kievit J, Tan MH, Fleuren GJ, Robinson BG, Delbridge LW, Philips J, Nelson AE, Krause U, Dralle H, Hoang-Vu C, Gimm O, Morreau H, Marsh DJ, Teh BT. Haven CJ, et al. Among authors: teh bt. Cancer Res. 2004 Oct 15;64(20):7405-11. doi: 10.1158/0008-5472.CAN-04-2063. Cancer Res. 2004. PMID: 15492263
502 results