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GSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synuclein.
Credle JJ, George JL, Wills J, Duka V, Shah K, Lee YC, Rodriguez O, Simkins T, Winter M, Moechars D, Steckler T, Goudreau J, Finkelstein DI, Sidhu A. Credle JJ, et al. Among authors: steckler t. Cell Death Differ. 2015 May;22(5):838-51. doi: 10.1038/cdd.2014.179. Epub 2014 Nov 14. Cell Death Differ. 2015. PMID: 25394490 Free PMC article.
IMPA1 is essential for embryonic development and lithium-like pilocarpine sensitivity.
Cryns K, Shamir A, Van Acker N, Levi I, Daneels G, Goris I, Bouwknecht JA, Andries L, Kass S, Agam G, Belmaker H, Bersudsky Y, Steckler T, Moechars D. Cryns K, et al. Among authors: steckler t. Neuropsychopharmacology. 2008 Feb;33(3):674-84. doi: 10.1038/sj.npp.1301431. Epub 2007 Apr 25. Neuropsychopharmacology. 2008. PMID: 17460611
Lack of lithium-like behavioral and molecular effects in IMPA2 knockout mice.
Cryns K, Shamir A, Shapiro J, Daneels G, Goris I, Van Craenendonck H, Straetemans R, Belmaker RH, Agam G, Moechars D, Steckler T. Cryns K, et al. Among authors: steckler t. Neuropsychopharmacology. 2007 Apr;32(4):881-91. doi: 10.1038/sj.npp.1301154. Epub 2006 Jul 12. Neuropsychopharmacology. 2007. PMID: 16841073
Touching on translation.
Talpos J, Steckler T. Talpos J, et al. Among authors: steckler t. Cell Tissue Res. 2013 Oct;354(1):297-308. doi: 10.1007/s00441-013-1694-7. Epub 2013 Aug 16. Cell Tissue Res. 2013. PMID: 23949375 Review.
190 results