Lowdell MW - Search Results

1

CMV-specific T cell isolation from G-CSF mobilized peripheral blood: depletion of myeloid progenitors eliminates non-specific binding of MHC-multimers.

Beloki L, Ciaurriz M, Mansilla C, Zabalza A, Perez-Valderrama E, Samuel ER, Lowdell MW, Ramirez N, Olavarria E. Beloki L, et al. Among authors: lowdell mw. J Transl Med. 2014 Nov 19;12:317. doi: 10.1186/s12967-014-0317-8. J Transl Med. 2014. PMID: 25406933 Free PMC article.

2

2-Phenylacetylenesulfonamide (PAS) induces p53-independent apoptotic killing of B-chronic lymphocytic leukemia (CLL) cells.

Steele AJ, Prentice AG, Hoffbrand AV, Yogashangary BC, Hart SM, Lowdell MW, Samuel ER, North JM, Nacheva EP, Chanalaris A, Kottaridis P, Cwynarski K, Wickremasinghe RG. Steele AJ, et al. Among authors: lowdell mw. Blood. 2009 Aug 6;114(6):1217-25. doi: 10.1182/blood-2008-11-190587. Epub 2009 Jun 10. Blood. 2009. PMID: 19515722 Free article.

3

Phase I study of high-stringency CD8 depletion of donor leukocyte infusions after allogeneic hematopoietic stem cell transplantation.

Orti G, Lowdell M, Fielding A, Samuel E, Pang K, Kottaridis P, Morris E, Thomson K, Peggs K, Mackinnon S, Chakraverty R. Orti G, et al. Transplantation. 2009 Dec 15;88(11):1312-8. doi: 10.1097/TP.0b013e3181bbf382. Transplantation. 2009. PMID: 19996931 Clinical Trial.

4

The JAK3-selective inhibitor PF-956980 reverses the resistance to cytotoxic agents induced by interleukin-4 treatment of chronic lymphocytic leukemia cells: potential for reversal of cytoprotection by the microenvironment.

Steele AJ, Prentice AG, Cwynarski K, Hoffbrand AV, Hart SM, Lowdell MW, Samuel ER, Wickremasinghe RG. Steele AJ, et al. Among authors: lowdell mw. Blood. 2010 Nov 25;116(22):4569-77. doi: 10.1182/blood-2009-09-245811. Epub 2010 Aug 17. Blood. 2010. PMID: 20716767 Free article.

5

Directly selected cytomegalovirus-reactive donor T cells confer rapid and safe systemic reconstitution of virus-specific immunity following stem cell transplantation.

Peggs KS, Thomson K, Samuel E, Dyer G, Armoogum J, Chakraverty R, Pang K, Mackinnon S, Lowdell MW. Peggs KS, et al. Among authors: lowdell mw. Clin Infect Dis. 2011 Jan 1;52(1):49-57. doi: 10.1093/cid/ciq042. Clin Infect Dis. 2011. PMID: 21148519 Clinical Trial.

6

Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study.

Elliott MJ, De Coppi P, Speggiorin S, Roebuck D, Butler CR, Samuel E, Crowley C, McLaren C, Fierens A, Vondrys D, Cochrane L, Jephson C, Janes S, Beaumont NJ, Cogan T, Bader A, Seifalian AM, Hsuan JJ, Lowdell MW, Birchall MA. Elliott MJ, et al. Among authors: lowdell mw. Lancet. 2012 Sep 15;380(9846):994-1000. doi: 10.1016/S0140-6736(12)60737-5. Epub 2012 Jul 26. Lancet. 2012. PMID: 22841419 Free PMC article.

7

Successful isolation and expansion of CMV-reactive T cells from G-CSF mobilized donors that retain a strong cytotoxic effector function.

Samuel ER, Newton K, Mackinnon S, Lowdell MW. Samuel ER, et al. Among authors: lowdell mw. Br J Haematol. 2013 Jan;160(1):87-100. doi: 10.1111/bjh.12082. Epub 2012 Oct 9. Br J Haematol. 2013. PMID: 23043413 Free article.

8

Isolation of highly suppressive CD25+FoxP3+ T regulatory cells from G-CSF-mobilized donors with retention of cytotoxic anti-viral CTLs: application for multi-functional immunotherapy post stem cell transplantation.

Samuel ER, Beloki L, Newton K, Mackinnon S, Lowdell MW. Samuel ER, et al. Among authors: lowdell mw. PLoS One. 2014 Jan 17;9(1):e85911. doi: 10.1371/journal.pone.0085911. eCollection 2014. PLoS One. 2014. PMID: 24465783 Free PMC article.

9

Manufacturing of highly functional and specific T cells for adoptive immunotherapy against virus from granulocyte colony-stimulating factor-mobilized donors.

Beloki L, Ramírez N, Olavarría E, Samuel ER, Lowdell MW. Beloki L, et al. Among authors: lowdell mw. Cytotherapy. 2014 Oct;16(10):1390-408. doi: 10.1016/j.jcyt.2014.05.009. Epub 2014 Jun 18. Cytotherapy. 2014. PMID: 24954783

10

Assessment of the effector function of CMV-specific CTLs isolated using MHC-multimers from granulocyte-colony stimulating factor mobilized peripheral blood.

Beloki L, Ciaurriz M, Mansilla C, Zabalza A, Perez-Valderrama E, Samuel ER, Lowdell MW, Ramirez N, Olavarria E. Beloki L, et al. Among authors: lowdell mw. J Transl Med. 2015 May 20;13:165. doi: 10.1186/s12967-015-0515-z. J Transl Med. 2015. PMID: 25990023 Free PMC article.

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