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Alterations in the antigen processing-presenting machinery of transformed plasma cells are associated with reduced recognition by CD8+ T cells and characterize the progression of MGUS to multiple myeloma.
Racanelli V, Leone P, Frassanito MA, Brunetti C, Perosa F, Ferrone S, Dammacco F. Racanelli V, et al. Among authors: dammacco f. Blood. 2010 Feb 11;115(6):1185-93. doi: 10.1182/blood-2009-06-228676. Epub 2009 Dec 11. Blood. 2010. PMID: 20008301 Free PMC article.
Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross-talk in the bone marrow of multiple myeloma patients.
Basile A, Moschetta M, Ditonno P, Ria R, Marech I, De Luisi A, Berardi S, Frassanito MA, Angelucci E, Derudas D, Specchia G, Curci P, Pavone V, Rossini B, Ribatti D, Bottazzi B, Mantovani A, Presta M, Dammacco F, Vacca A. Basile A, et al. Among authors: dammacco f. J Pathol. 2013 Jan;229(1):87-98. doi: 10.1002/path.4081. Epub 2012 Oct 1. J Pathol. 2013. PMID: 22847671 Free article.
HIF-1α of bone marrow endothelial cells implies relapse and drug resistance in patients with multiple myeloma and may act as a therapeutic target.
Ria R, Catacchio I, Berardi S, De Luisi A, Caivano A, Piccoli C, Ruggieri V, Frassanito MA, Ribatti D, Nico B, Annese T, Ruggieri S, Guarini A, Minoia C, Ditonno P, Angelucci E, Derudas D, Moschetta M, Dammacco F, Vacca A. Ria R, et al. Among authors: dammacco f. Clin Cancer Res. 2014 Feb 15;20(4):847-58. doi: 10.1158/1078-0432.CCR-13-1950. Epub 2013 Dec 2. Clin Cancer Res. 2014. PMID: 24297864
512 results