Högenauer K - Search Results

1

G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonists reduce the production of proinflammatory cytokines and stabilize the alternative macrophage phenotype.

Högenauer K, Arista L, Schmiedeberg N, Werner G, Jaksche H, Bouhelal R, Nguyen DG, Bhat BG, Raad L, Rauld C, Carballido JM. Högenauer K, et al. J Med Chem. 2014 Dec 26;57(24):10343-54. doi: 10.1021/jm501052c. Epub 2014 Dec 9. J Med Chem. 2014. PMID: 25411721

2

S1P receptor mediated activity of FTY720 phosphate mimics.

Högenauer K, Hinterding K, Nussbaumer P. Högenauer K, et al. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1485-7. doi: 10.1016/j.bmcl.2010.01.118. Epub 2010 Jan 28. Bioorg Med Chem Lett. 2010. PMID: 20153186

3

Synthesis of borondipyrromethene (BODIPY)-labeled sphingosine derivatives by cross-metathesis reaction.

Peters C, Billich A, Ghobrial M, Högenauer K, Ullrich T, Nussbaumer P. Peters C, et al. Among authors: hogenauer k. J Org Chem. 2007 Mar 2;72(5):1842-5. doi: 10.1021/jo062347b. Epub 2007 Jan 24. J Org Chem. 2007. PMID: 17249735

4

Phosphorylation by sphingosine kinase 2 is essential for in vivo potency of FTY720 analogues.

Högenauer K, Billich A, Pally C, Streiff M, Wagner T, Welzenbach K, Nussbaumer P. Högenauer K, et al. ChemMedChem. 2008 Jul;3(7):1027-9. doi: 10.1002/cmdc.200800037. ChemMedChem. 2008. PMID: 18383466 No abstract available.

5

One-step labelling of sphingolipids via a scrambling cross-metathesis reaction.

Nussbaumer P, Ettmayer P, Peters C, Rosenbeiger D, Högenauer K. Nussbaumer P, et al. Among authors: hogenauer k. Chem Commun (Camb). 2005 Oct 28;(40):5086-7. doi: 10.1039/b508132g. Epub 2005 Sep 14. Chem Commun (Camb). 2005. PMID: 16220179

6

Synthesis and acetylcholinesterase inhibition of 5-desamino huperzine A derivatives.

Högenauer K, Baumann K, Enz A, Mulzer J. Högenauer K, et al. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2627-30. doi: 10.1016/s0960-894x(01)00518-2. Bioorg Med Chem Lett. 2001. PMID: 11551765

7

A novel palladium-catalyzed intramolecular redox reaction.

Högenauer K, Mulzer J. Högenauer K, et al. Org Lett. 2001 May 17;3(10):1495-7. doi: 10.1021/ol015813m. Org Lett. 2001. PMID: 11388850

8

Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition.

Andrews SP, Ball M, Wierschem F, Cleator E, Oliver S, Högenauer K, Simic O, Antonello A, Hünger U, Smith MD, Ley SV. Andrews SP, et al. Among authors: hogenauer k. Chemistry. 2007;13(20):5688-712. doi: 10.1002/chem.200700302. Chemistry. 2007. PMID: 17508363

9

Synthesis of the thapsigargins.

Ley SV, Antonello A, Balskus EP, Booth DT, Christensen SB, Cleator E, Gold H, Högenauer K, Hünger U, Myers RM, Oliver SF, Simic O, Smith MD, Søhoel H, Woolford AJ. Ley SV, et al. Among authors: hogenauer k. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12073-8. doi: 10.1073/pnas.0403300101. Epub 2004 Jun 28. Proc Natl Acad Sci U S A. 2004. PMID: 15226504 Free PMC article.

10

A route to the thapsigargins from (S)-carvone providing a substrate-controlled total synthesis of trilobolide, nortrilobolide, and thapsivillosin F.

Oliver SF, Högenauer K, Simic O, Antonello A, Smith MD, Ley SV. Oliver SF, et al. Among authors: hogenauer k. Angew Chem Int Ed Engl. 2003 Dec 15;42(48):5996-6000. doi: 10.1002/anie.200353140. Angew Chem Int Ed Engl. 2003. PMID: 14679553 No abstract available.

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