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FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis.
Zhao X, Yang Y, Sun BF, Shi Y, Yang X, Xiao W, Hao YJ, Ping XL, Chen YS, Wang WJ, Jin KX, Wang X, Huang CM, Fu Y, Ge XM, Song SH, Jeong HS, Yanagisawa H, Niu Y, Jia GF, Wu W, Tong WM, Okamoto A, He C, Rendtlew Danielsen JM, Wang XJ, Yang YG. Zhao X, et al. Among authors: wang x, wang xj, wang wj. Cell Res. 2014 Dec;24(12):1403-19. doi: 10.1038/cr.2014.151. Epub 2014 Nov 21. Cell Res. 2014. PMID: 25412662 Free PMC article.
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Zheng G, Dahl JA, Niu Y, Fedorcsak P, Huang CM, Li CJ, Vågbø CB, Shi Y, Wang WL, Song SH, Lu Z, Bosmans RP, Dai Q, Hao YJ, Yang X, Zhao WM, Tong WM, Wang XJ, Bogdan F, Furu K, Fu Y, Jia G, Zhao X, Liu J, Krokan HE, Klungland A, Yang YG, He C. Zheng G, et al. Among authors: wang xj, wang wl. Mol Cell. 2013 Jan 10;49(1):18-29. doi: 10.1016/j.molcel.2012.10.015. Epub 2012 Nov 21. Mol Cell. 2013. PMID: 23177736 Free PMC article.
Parthenogenetic haploid embryonic stem cells produce fertile mice.
Wan H, He Z, Dong M, Gu T, Luo GZ, Teng F, Xia B, Li W, Feng C, Li X, Li T, Shuai L, Fu R, Wang L, Wang XJ, Zhao XY, Zhou Q. Wan H, et al. Among authors: wang l, wang xj. Cell Res. 2013 Nov;23(11):1330-3. doi: 10.1038/cr.2013.126. Epub 2013 Sep 10. Cell Res. 2013. PMID: 24018377 Free PMC article. No abstract available.
m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency.
Chen T, Hao YJ, Zhang Y, Li MM, Wang M, Han W, Wu Y, Lv Y, Hao J, Wang L, Li A, Yang Y, Jin KX, Zhao X, Li Y, Ping XL, Lai WY, Wu LG, Jiang G, Wang HL, Sang L, Wang XJ, Yang YG, Zhou Q. Chen T, et al. Among authors: wang l, wang xj, wang hl, wang m. Cell Stem Cell. 2015 Mar 5;16(3):289-301. doi: 10.1016/j.stem.2015.01.016. Epub 2015 Feb 12. Cell Stem Cell. 2015. PMID: 25683224 Free article.
Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
Xiao W, Adhikari S, Dahal U, Chen YS, Hao YJ, Sun BF, Sun HY, Li A, Ping XL, Lai WY, Wang X, Ma HL, Huang CM, Yang Y, Huang N, Jiang GB, Wang HL, Zhou Q, Wang XJ, Zhao YL, Yang YG. Xiao W, et al. Among authors: wang x, wang xj, wang hl. Mol Cell. 2016 Feb 18;61(4):507-519. doi: 10.1016/j.molcel.2016.01.012. Epub 2016 Feb 11. Mol Cell. 2016. PMID: 26876937 Free article.
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