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Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth.
Haubrich BA, Singha UK, Miller MB, Nes CR, Anyatonwu H, Lecordier L, Patkar P, Leaver DJ, Villalta F, Vanhollebeke B, Chaudhuri M, Nes WD. Haubrich BA, et al. Among authors: vanhollebeke b. J Lipid Res. 2015 Feb;56(2):331-41. doi: 10.1194/jlr.M054643. Epub 2014 Nov 25. J Lipid Res. 2015. PMID: 25424002 Free PMC article.
Crystal structures of Trypanosoma brucei sterol 14alpha-demethylase and implications for selective treatment of human infections.
Lepesheva GI, Park HW, Hargrove TY, Vanhollebeke B, Wawrzak Z, Harp JM, Sundaramoorthy M, Nes WD, Pays E, Chaudhuri M, Villalta F, Waterman MR. Lepesheva GI, et al. Among authors: vanhollebeke b. J Biol Chem. 2010 Jan 15;285(3):1773-80. doi: 10.1074/jbc.M109.067470. Epub 2009 Nov 18. J Biol Chem. 2010. PMID: 19923211 Free PMC article.
Mechanism of Trypanosoma brucei gambiense resistance to human serum.
Uzureau P, Uzureau S, Lecordier L, Fontaine F, Tebabi P, Homblé F, Grélard A, Zhendre V, Nolan DP, Lins L, Crowet JM, Pays A, Felu C, Poelvoorde P, Vanhollebeke B, Moestrup SK, Lyngsø J, Pedersen JS, Mottram JC, Dufourc EJ, Pérez-Morga D, Pays E. Uzureau P, et al. Among authors: vanhollebeke b. Nature. 2013 Sep 19;501(7467):430-4. doi: 10.1038/nature12516. Epub 2013 Aug 21. Nature. 2013. PMID: 23965626
The molecular arms race between African trypanosomes and humans.
Pays E, Vanhollebeke B, Uzureau P, Lecordier L, Pérez-Morga D. Pays E, et al. Among authors: vanhollebeke b. Nat Rev Microbiol. 2014 Aug;12(8):575-84. doi: 10.1038/nrmicro3298. Epub 2014 Jun 30. Nat Rev Microbiol. 2014. PMID: 24975321 Review.
APOLs with low pH dependence can kill all African trypanosomes.
Fontaine F, Lecordier L, Vanwalleghem G, Uzureau P, Van Reet N, Fontaine M, Tebabi P, Vanhollebeke B, Büscher P, Pérez-Morga D, Pays E. Fontaine F, et al. Among authors: vanhollebeke b. Nat Microbiol. 2017 Nov;2(11):1500-1506. doi: 10.1038/s41564-017-0034-1. Epub 2017 Sep 18. Nat Microbiol. 2017. PMID: 28924146 Free PMC article.
The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity.
Lecordier L, Uzureau S, Vanwalleghem G, Deleu M, Crowet JM, Barry P, Moran B, Voorheis P, Dumitru AC, Yamaryo-Botté Y, Dieu M, Tebabi P, Vanhollebeke B, Lins L, Botté CY, Alsteens D, Dufrêne Y, Pérez-Morga D, Nolan DP, Pays E. Lecordier L, et al. Among authors: vanhollebeke b. iScience. 2020 Aug 20;23(9):101476. doi: 10.1016/j.isci.2020.101476. eCollection 2020 Sep 25. iScience. 2020. PMID: 32889430 Free PMC article.
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