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Acetylation targets mutant huntingtin to autophagosomes for degradation.
Jeong H, Then F, Melia TJ Jr, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Jeong H, et al. Among authors: voisine c. Cell. 2009 Apr 3;137(1):60-72. doi: 10.1016/j.cell.2009.03.018. Cell. 2009. PMID: 19345187 Free PMC article.
Inhibitors of metabolism rescue cell death in Huntington's disease models.
Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR. Varma H, et al. Among authors: voisine c. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14525-30. doi: 10.1073/pnas.0704482104. Epub 2007 Aug 28. Proc Natl Acad Sci U S A. 2007. PMID: 17726098 Free PMC article.
Selective inhibitors of death in mutant huntingtin cells.
Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Varma H, et al. Among authors: voisine c. Nat Chem Biol. 2007 Feb;3(2):99-100. doi: 10.1038/nchembio852. Epub 2006 Dec 31. Nat Chem Biol. 2007. PMID: 17195849
40 results