Xue L - Search Results

1

Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.

Xue L, Fergusson J, Salimi M, Panse I, Ussher JE, Hegazy AN, Vinall SL, Jackson DG, Hunter MG, Pettipher R, Ogg G, Klenerman P. Xue L, et al. J Allergy Clin Immunol. 2015 May;135(5):1358-66.e1-11. doi: 10.1016/j.jaci.2014.09.006. Epub 2014 Oct 19. J Allergy Clin Immunol. 2015. PMID: 25441644 Free PMC article.

2

Interaction between prostaglandin D and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells.

Xue L, Barrow A, Pettipher R. Xue L, et al. Clin Exp Immunol. 2009 Apr;156(1):126-33. doi: 10.1111/j.1365-2249.2008.03871.x. Epub 2009 Feb 11. Clin Exp Immunol. 2009. PMID: 19220324 Free PMC article.

3

Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2.

Xue L, Barrow A, Fleming VM, Hunter MG, Ogg G, Klenerman P, Pettipher R. Xue L, et al. J Immunol. 2012 Jan 15;188(2):694-702. doi: 10.4049/jimmunol.1102474. Epub 2011 Dec 14. J Immunol. 2012. PMID: 22174450 Free PMC article.

4

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells.

Xue L, Salimi M, Panse I, Mjösberg JM, McKenzie AN, Spits H, Klenerman P, Ogg G. Xue L, et al. J Allergy Clin Immunol. 2014 Apr;133(4):1184-94. doi: 10.1016/j.jaci.2013.10.056. Epub 2013 Dec 31. J Allergy Clin Immunol. 2014. PMID: 24388011 Free PMC article.

5

Cysteinyl leukotriene E₄ activates human group 2 innate lymphoid cells and enhances the effect of prostaglandin D₂ and epithelial cytokines.

Salimi M, Stöger L, Liu W, Go S, Pavord I, Klenerman P, Ogg G, Xue L. Salimi M, et al. Among authors: xue l. J Allergy Clin Immunol. 2017 Oct;140(4):1090-1100.e11. doi: 10.1016/j.jaci.2016.12.958. Epub 2017 Jan 20. J Allergy Clin Immunol. 2017. PMID: 28115217 Free PMC article.

6

Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.

Xue L, Gyles SL, Wettey FR, Gazi L, Townsend E, Hunter MG, Pettipher R. Xue L, et al. J Immunol. 2005 Nov 15;175(10):6531-6. doi: 10.4049/jimmunol.175.10.6531. J Immunol. 2005. PMID: 16272307

7

CRTH2 mediates the activation of human Th2 cells in response to PGD(2) released from IgE/anti-IgE treated nasal polyp tissue.

Pérez-Novo CA, Holtappels G, Vinall SL, Xue L, Zhang N, Bachert C, Pettipher R. Pérez-Novo CA, et al. Among authors: xue l. Allergy. 2010 Mar;65(3):304-10. doi: 10.1111/j.1398-9995.2009.02204.x. Epub 2009 Oct 12. Allergy. 2010. PMID: 19839971

8

Resistance to apoptosis underpins the corticosteroid insensitivity of group 2 innate lymphoid cells.

Luo J, Wu Y, Shrimanker R, Go S, Ye Y, Hardman C, Nahler J, Chen YL, Stöger L, Zeng N, Liu W, Reed L, Tolkovsky AM, Klenerman P, Ogg G, Pavord ID, Xue L. Luo J, et al. Among authors: xue l. J Allergy Clin Immunol. 2019 Dec;144(6):1722-1726.e10. doi: 10.1016/j.jaci.2019.08.008. Epub 2019 Aug 22. J Allergy Clin Immunol. 2019. PMID: 31445099 No abstract available.

9

A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.

Gyles SL, Xue L, Townsend ER, Wettey F, Pettipher R. Gyles SL, et al. Among authors: xue l. Immunology. 2006 Nov;119(3):362-8. doi: 10.1111/j.1365-2567.2006.02440.x. Immunology. 2006. PMID: 17067313 Free PMC article.

10

Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D(2).

Xue L, Gyles SL, Barrow A, Pettipher R. Xue L, et al. Biochem Pharmacol. 2007 Mar 15;73(6):843-53. doi: 10.1016/j.bcp.2006.11.021. Epub 2006 Dec 1. Biochem Pharmacol. 2007. PMID: 17196174

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