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A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity.
Joyce PI, Mcgoldrick P, Saccon RA, Weber W, Fratta P, West SJ, Zhu N, Carter S, Phatak V, Stewart M, Simon M, Kumar S, Heise I, Bros-Facer V, Dick J, Corrochano S, Stanford MJ, Luong TV, Nolan PM, Meyer T, Brandner S, Bennett DL, Ozdinler PH, Greensmith L, Fisher EM, Acevedo-Arozena A. Joyce PI, et al. Hum Mol Genet. 2015 Apr 1;24(7):1883-97. doi: 10.1093/hmg/ddu605. Epub 2014 Dec 2. Hum Mol Genet. 2015. PMID: 25468678 Free PMC article.
ENU mutagenesis, a way forward to understand gene function.
Acevedo-Arozena A, Wells S, Potter P, Kelly M, Cox RD, Brown SD. Acevedo-Arozena A, et al. Annu Rev Genomics Hum Genet. 2008;9:49-69. doi: 10.1146/annurev.genom.9.081307.164224. Annu Rev Genomics Hum Genet. 2008. PMID: 18949851 Review.
Behavioral and other phenotypes in a cytoplasmic Dynein light intermediate chain 1 mutant mouse.
Banks GT, Haas MA, Line S, Shepherd HL, Alqatari M, Stewart S, Rishal I, Philpott A, Kalmar B, Kuta A, Groves M, Parkinson N, Acevedo-Arozena A, Brandner S, Bannerman D, Greensmith L, Hafezparast M, Koltzenburg M, Deacon R, Fainzilber M, Fisher EM. Banks GT, et al. J Neurosci. 2011 Apr 6;31(14):5483-94. doi: 10.1523/JNEUROSCI.5244-10.2011. J Neurosci. 2011. PMID: 21471385 Free PMC article.
α-Synuclein levels modulate Huntington's disease in mice.
Corrochano S, Renna M, Carter S, Chrobot N, Kent R, Stewart M, Cooper J, Brown SD, Rubinsztein DC, Acevedo-Arozena A. Corrochano S, et al. Hum Mol Genet. 2012 Feb 1;21(3):485-94. doi: 10.1093/hmg/ddr477. Epub 2011 Oct 18. Hum Mol Genet. 2012. PMID: 22010050 Free PMC article.
IGF-1 receptor antagonism inhibits autophagy.
Renna M, Bento CF, Fleming A, Menzies FM, Siddiqi FH, Ravikumar B, Puri C, Garcia-Arencibia M, Sadiq O, Corrochano S, Carter S, Brown SD, Acevedo-Arozena A, Rubinsztein DC. Renna M, et al. Hum Mol Genet. 2013 Nov 15;22(22):4528-44. doi: 10.1093/hmg/ddt300. Epub 2013 Jun 25. Hum Mol Genet. 2013. PMID: 23804751 Free PMC article.
39 results