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LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression.
Feig JE, Pineda-Torra I, Sanson M, Bradley MN, Vengrenyuk Y, Bogunovic D, Gautier EL, Rubinstein D, Hong C, Liu J, Wu C, van Rooijen N, Bhardwaj N, Garabedian M, Tontonoz P, Fisher EA. Feig JE, et al. Among authors: vengrenyuk y. J Clin Invest. 2010 Dec;120(12):4415-24. doi: 10.1172/JCI38911. J Clin Invest. 2010. PMID: 21041949 Free PMC article.
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR. Westerterp M, et al. Among authors: vengrenyuk y. Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9. Circ Res. 2013. PMID: 23572498 Free PMC article.
Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.
Vengrenyuk Y, Nishi H, Long X, Ouimet M, Savji N, Martinez FO, Cassella CP, Moore KJ, Ramsey SA, Miano JM, Fisher EA. Vengrenyuk Y, et al. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):535-46. doi: 10.1161/ATVBAHA.114.304029. Epub 2015 Jan 8. Arterioscler Thromb Vasc Biol. 2015. PMID: 25573853 Free PMC article.
65 results