Wennerberg K - Search Results

1

Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.

van Adrichem AJ, Fagerholm A, Turunen L, Lehto A, Saarela J, Koskinen A, Repasky GA, Wennerberg K. van Adrichem AJ, et al. Among authors: wennerberg k. Comb Chem High Throughput Screen. 2015;18(1):3-17. doi: 10.2174/1386207318666141205112730. Comb Chem High Throughput Screen. 2015. PMID: 25479424 Free PMC article.

2

The inconvenience of data of convenience: computational research beyond post-mortem analyses.

Azencott CA, Aittokallio T, Roy S; DREAM Idea Challenge Consortium; Norman T, Friend S, Stolovitzky G, Goldenberg A. Azencott CA, et al. Nat Methods. 2017 Sep 29;14(10):937-938. doi: 10.1038/nmeth.4457. Nat Methods. 2017. PMID: 28960198 No abstract available.

3

PP2A-based triple-strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells.

Denisova OV, Merisaari J, Huhtaniemi R, Qiao X, Yetukuri L, Jumppanen M, Kaur A, Pääkkönen M, von Schantz-Fant С, Ohlmeyer M, Wennerberg K, Kauko O, Koch R, Aittokallio T, Taipale M, Westermarck J. Denisova OV, et al. Among authors: wennerberg k. Mol Oncol. 2023 Sep;17(9):1803-1820. doi: 10.1002/1878-0261.13488. Epub 2023 Jul 26. Mol Oncol. 2023. PMID: 37458534 Free PMC article.

4

Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.

Klomp JA, Klomp JE, Stalnecker CA, Bryant KL, Edwards AC, Drizyte-Miller K, Hibshman PS, Diehl JN, Lee YS, Morales AJ, Taylor KE, Peng S, Tran NL, Herring LE, Prevatte AW, Barker NK, Hover LD, Hallin J, Sorokin A, Kanikarla PM, Chowdhury S, Coker O, Lee HM, Goodwin CM, Gautam P, Olson P, Christensen JG, Shen JP, Kopetz S, Graves LM, Lim KH, Wang-Gillam A, Wennerberg K, Cox AD, Der CJ. Klomp JA, et al. Among authors: wennerberg k. Science. 2024 Jun 7;384(6700):eadk0775. doi: 10.1126/science.adk0775. Epub 2024 Jun 7. Science. 2024. PMID: 38843331 Free PMC article.

5

Somatic STAT3 mutations in large granular lymphocytic leukemia.

Koskela HL, Eldfors S, Ellonen P, van Adrichem AJ, Kuusanmäki H, Andersson EI, Lagström S, Clemente MJ, Olson T, Jalkanen SE, Majumder MM, Almusa H, Edgren H, Lepistö M, Mattila P, Guinta K, Koistinen P, Kuittinen T, Penttinen K, Parsons A, Knowles J, Saarela J, Wennerberg K, Kallioniemi O, Porkka K, Loughran TP Jr, Heckman CA, Maciejewski JP, Mustjoki S. Koskela HL, et al. Among authors: wennerberg k. N Engl J Med. 2012 May 17;366(20):1905-13. doi: 10.1056/NEJMoa1114885. N Engl J Med. 2012. PMID: 22591296 Free PMC article.

6

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia.

Rajala HL, Eldfors S, Kuusanmäki H, van Adrichem AJ, Olson T, Lagström S, Andersson EI, Jerez A, Clemente MJ, Yan Y, Zhang D, Awwad A, Ellonen P, Kallioniemi O, Wennerberg K, Porkka K, Maciejewski JP, Loughran TP Jr, Heckman C, Mustjoki S. Rajala HL, et al. Among authors: wennerberg k. Blood. 2013 May 30;121(22):4541-50. doi: 10.1182/blood-2012-12-474577. Epub 2013 Apr 17. Blood. 2013. PMID: 23596048 Free PMC article.

7

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

Pemovska T, Kontro M, Yadav B, Edgren H, Eldfors S, Szwajda A, Almusa H, Bespalov MM, Ellonen P, Elonen E, Gjertsen BT, Karjalainen R, Kulesskiy E, Lagström S, Lehto A, Lepistö M, Lundán T, Majumder MM, Marti JM, Mattila P, Murumägi A, Mustjoki S, Palva A, Parsons A, Pirttinen T, Rämet ME, Suvela M, Turunen L, Västrik I, Wolf M, Knowles J, Aittokallio T, Heckman CA, Porkka K, Kallioniemi O, Wennerberg K. Pemovska T, et al. Among authors: wennerberg k. Cancer Discov. 2013 Dec;3(12):1416-29. doi: 10.1158/2159-8290.CD-13-0350. Epub 2013 Sep 20. Cancer Discov. 2013. PMID: 24056683

8

Utilization of in situ ELISA method for examining Trk receptor phosphorylation in cultured cells.

Antila H, Autio H, Turunen L, Harju K, Tammela P, Wennerberg K, Yli-Kauhaluoma J, Huttunen HJ, Castrén E, Rantamäki T. Antila H, et al. Among authors: wennerberg k. J Neurosci Methods. 2014 Jan 30;222:142-6. doi: 10.1016/j.jneumeth.2013.11.001. Epub 2013 Nov 12. J Neurosci Methods. 2014. PMID: 24239780 Free article.

9

The high throughput biomedicine unit at the institute for molecular medicine Finland: high throughput screening meets precision medicine.

Pietiainen V, Saarela J, von Schantz C, Turunen L, Ostling P, Wennerberg K. Pietiainen V, et al. Among authors: wennerberg k. Comb Chem High Throughput Screen. 2014 May;17(4):377-86. doi: 10.2174/1386207317666140323195927. Comb Chem High Throughput Screen. 2014. PMID: 24661208

10

Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.

Pemovska T, Johnson E, Kontro M, Repasky GA, Chen J, Wells P, Cronin CN, McTigue M, Kallioniemi O, Porkka K, Murray BW, Wennerberg K. Pemovska T, et al. Among authors: wennerberg k. Nature. 2015 Mar 5;519(7541):102-5. doi: 10.1038/nature14119. Epub 2015 Feb 9. Nature. 2015. PMID: 25686603

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