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Leptin mediates the increase in blood pressure associated with obesity.
Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O'Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA. Simonds SE, et al. Cell. 2014 Dec 4;159(6):1404-16. doi: 10.1016/j.cell.2014.10.058. Cell. 2014. PMID: 25480301 Free PMC article.
Early nutrition and leptin concentrations in later life.
Singhal A, Farooqi IS, O'Rahilly S, Cole TJ, Fewtrell M, Lucas A. Singhal A, et al. Am J Clin Nutr. 2002 Jun;75(6):993-9. doi: 10.1093/ajcn/75.6.993. Am J Clin Nutr. 2002. PMID: 12036804 Clinical Trial.
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance.
Lee YS, Challis BG, Thompson DA, Yeo GS, Keogh JM, Madonna ME, Wraight V, Sims M, Vatin V, Meyre D, Shield J, Burren C, Ibrahim Z, Cheetham T, Swift P, Blackwood A, Hung CC, Wareham NJ, Froguel P, Millhauser GL, O'Rahilly S, Farooqi IS. Lee YS, et al. Cell Metab. 2006 Feb;3(2):135-40. doi: 10.1016/j.cmet.2006.01.006. Cell Metab. 2006. PMID: 16459314 Free article.
Genetics of obesity.
O'Rahilly S, Farooqi IS. O'Rahilly S, et al. Philos Trans R Soc Lond B Biol Sci. 2006 Jul 29;361(1471):1095-105. doi: 10.1098/rstb.2006.1850. Philos Trans R Soc Lond B Biol Sci. 2006. PMID: 16815794 Free PMC article. Review.
Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.
Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, Marais D, Schwabe J, Barroso I, Trembath R, Wareham N, Nagy L, Gurnell M, O'Rahilly S, Chatterjee K. Agostini M, et al. Cell Metab. 2006 Oct;4(4):303-11. doi: 10.1016/j.cmet.2006.09.003. Cell Metab. 2006. PMID: 17011503 Free PMC article.
Genetics of obesity in humans.
Farooqi S, O'Rahilly S. Farooqi S, et al. Endocr Rev. 2006 Dec;27(7):710-18. doi: 10.1210/er.2006-0040. Epub 2006 Nov 22. Endocr Rev. 2006. PMID: 17122358 Review.
558 results