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Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria.
Lau CK, Turner L, Jespersen JS, Lowe ED, Petersen B, Wang CW, Petersen JE, Lusingu J, Theander TG, Lavstsen T, Higgins MK. Lau CK, et al. Among authors: petersen b, petersen je. Cell Host Microbe. 2015 Jan 14;17(1):118-29. doi: 10.1016/j.chom.2014.11.007. Epub 2014 Dec 4. Cell Host Microbe. 2015. PMID: 25482433 Free PMC article.
Severe malaria is associated with parasite binding to endothelial protein C receptor.
Turner L, Lavstsen T, Berger SS, Wang CW, Petersen JE, Avril M, Brazier AJ, Freeth J, Jespersen JS, Nielsen MA, Magistrado P, Lusingu J, Smith JD, Higgins MK, Theander TG. Turner L, et al. Among authors: petersen je. Nature. 2013 Jun 27;498(7455):502-5. doi: 10.1038/nature12216. Epub 2013 Jun 5. Nature. 2013. PMID: 23739325 Free PMC article.
Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.
Berger SS, Turner L, Wang CW, Petersen JE, Kraft M, Lusingu JP, Mmbando B, Marquard AM, Bengtsson DB, Hviid L, Nielsen MA, Theander TG, Lavstsen T. Berger SS, et al. Among authors: petersen je. PLoS One. 2013 Jul 9;8(7):e69117. doi: 10.1371/journal.pone.0069117. Print 2013. PLoS One. 2013. PMID: 23874884 Free PMC article.
Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Lennartz F, Adams Y, Bengtsson A, Olsen RW, Turner L, Ndam NT, Ecklu-Mensah G, Moussiliou A, Ofori MF, Gamain B, Lusingu JP, Petersen JE, Wang CW, Nunes-Silva S, Jespersen JS, Lau CK, Theander TG, Lavstsen T, Hviid L, Higgins MK, Jensen AT. Lennartz F, et al. Among authors: petersen je. Cell Host Microbe. 2017 Mar 8;21(3):403-414. doi: 10.1016/j.chom.2017.02.009. Cell Host Microbe. 2017. PMID: 28279348 Free PMC article.
Cytoadhesion to gC1qR through Plasmodium falciparum Erythrocyte Membrane Protein 1 in Severe Malaria.
Magallón-Tejada A, Machevo S, Cisteró P, Lavstsen T, Aide P, Rubio M, Jiménez A, Turner L, Valmaseda A, Gupta H, De Las Salas B, Mandomando I, Wang CW, Petersen JE, Muñoz J, Gascón J, Macete E, Alonso PL, Chitnis CE, Bassat Q, Mayor A. Magallón-Tejada A, et al. Among authors: petersen je. PLoS Pathog. 2016 Nov 11;12(11):e1006011. doi: 10.1371/journal.ppat.1006011. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27835682 Free PMC article.
Breaking down brain barrier breaches in cerebral malaria.
Petersen JE, Lavstsen T, Craig A. Petersen JE, et al. J Clin Invest. 2016 Oct 3;126(10):3725-3727. doi: 10.1172/JCI90188. Epub 2016 Sep 19. J Clin Invest. 2016. PMID: 27643435 Free PMC article.
56 results