Geng M - Search Results

1

Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity.

Ren J, Yang M, Liu H, Cao D, Chen D, Li J, Tang L, He J, Chen YL, Geng M, Xiong B, Shen J. Ren J, et al. Among authors: geng m. Org Biomol Chem. 2015 Feb 7;13(5):1531-5. doi: 10.1039/c4ob01865f. Org Biomol Chem. 2015. PMID: 25490978

2

Salvicine functions as novel topoisomerase II poison by binding to ATP pocket.

Hu CX, Zuo ZL, Xiong B, Ma JG, Geng MY, Lin LP, Jiang HL, Ding J. Hu CX, et al. Mol Pharmacol. 2006 Nov;70(5):1593-601. doi: 10.1124/mol.106.027714. Epub 2006 Aug 16. Mol Pharmacol. 2006. PMID: 16914642

3

Trigochinins A-C: three new daphnane-type diterpenes from Trigonostemon chinensis.

Chen HD, Yang SP, He XF, Ai J, Liu ZK, Liu HB, Geng MY, Yue JM. Chen HD, et al. Org Lett. 2010 Mar 19;12(6):1168-71. doi: 10.1021/ol9028995. Org Lett. 2010. PMID: 20148570

4

Synthesis and antitumor activity of 10-arylcamptothecin derivatives.

Jiao Y, Liu H, Geng M, Duan W. Jiao Y, et al. Among authors: geng m. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2071-4. doi: 10.1016/j.bmcl.2011.02.005. Epub 2011 Feb 16. Bioorg Med Chem Lett. 2011. PMID: 21333532

5

Expeditious one-pot synthesis of C3-piperazinyl-substituted quinolines: key precursors to potent c-Met inhibitors.

Wang Y, Ai J, Liu G, Geng M, Zhang A. Wang Y, et al. Among authors: geng m. Org Biomol Chem. 2011 Sep 7;9(17):5930-3. doi: 10.1039/c1ob05830d. Epub 2011 Jul 25. Org Biomol Chem. 2011. PMID: 21785792

6

Discovering potent inhibitors against c-Met kinase: molecular design, organic synthesis and bioassay.

Liang Z, Ding X, Ai J, Kong X, Chen L, Chen L, Luo C, Geng M, Liu H, Chen K, Jiang H. Liang Z, et al. Among authors: geng m. Org Biomol Chem. 2012 Jan 14;10(2):421-30. doi: 10.1039/c1ob06186k. Epub 2011 Nov 23. Org Biomol Chem. 2012. PMID: 22108637

7

Discovery of 3H-imidazo[4,5-b]pyridines as potent c-Met kinase inhibitors: design, synthesis, and biological evaluation.

Chen D, Wang Y, Ma Y, Xiong B, Ai J, Chen Y, Geng M, Shen J. Chen D, et al. Among authors: geng m. ChemMedChem. 2012 Jun;7(6):1057-70. doi: 10.1002/cmdc.201200120. Epub 2012 May 13. ChemMedChem. 2012. PMID: 22581753

8

Evaluation of the cytotoxic activity of new jadomycin derivatives reveals the potential to improve its selectivity against tumor cells.

Fan K, Zhang X, Liu H, Han H, Luo Y, Wang Q, Geng M, Yang K. Fan K, et al. Among authors: geng m. J Antibiot (Tokyo). 2012 Sep;65(9):449-52. doi: 10.1038/ja.2012.48. Epub 2012 Jun 20. J Antibiot (Tokyo). 2012. PMID: 22714025

9

Investigation on the 1,6-naphthyridine motif: discovery and SAR study of 1H-imidazo[4,5-h][1,6]naphthyridin-2(3H)-one-based c-Met kinase inhibitors.

Wang Y, Xu ZL, Ai J, Peng X, Lin JP, Ji YC, Geng MY, Long YQ. Wang Y, et al. Org Biomol Chem. 2013 Mar 7;11(9):1545-62. doi: 10.1039/c2ob26710a. Org Biomol Chem. 2013. PMID: 23188156

10

Energetic factors determining the binding of type I inhibitors to c-Met kinase: experimental studies and quantum mechanical calculations.

Yu Z, Ma YC, Ai J, Chen DQ, Zhao DM, Wang X, Chen YL, Geng MY, Xiong B, Cheng MS, Shen JK. Yu Z, et al. Acta Pharmacol Sin. 2013 Nov;34(11):1475-83. doi: 10.1038/aps.2013.85. Epub 2013 Sep 23. Acta Pharmacol Sin. 2013. PMID: 24056705 Free PMC article.

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