Shen J - Search Results

1

Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity.

Ren J, Yang M, Liu H, Cao D, Chen D, Li J, Tang L, He J, Chen YL, Geng M, Xiong B, Shen J. Ren J, et al. Among authors: shen j. Org Biomol Chem. 2015 Feb 7;13(5):1531-5. doi: 10.1039/c4ob01865f. Org Biomol Chem. 2015. PMID: 25490978

2

Inhibitory mode of 1,5-diarylpyrazole derivatives against cyclooxygenase-2 and cyclooxygenase-1: molecular docking and 3D QSAR analyses.

Liu H, Huang X, Shen J, Luo X, Li M, Xiong B, Chen G, Shen J, Yang Y, Jiang H, Chen K. Liu H, et al. Among authors: shen j. J Med Chem. 2002 Oct 24;45(22):4816-27. doi: 10.1021/jm020089e. J Med Chem. 2002. PMID: 12383007

3

One novel quinoxaline derivative as a potent human cyclophilin A inhibitor shows highly inhibitory activity against mouse spleen cell proliferation.

Li J, Chen J, Zhang L, Wang F, Gui C, Zhang L, Qin Y, Xu Q, Liu H, Nan F, Shen J, Bai D, Chen K, Shen X, Jiang H. Li J, et al. Among authors: shen x, shen j. Bioorg Med Chem. 2006 Aug 15;14(16):5527-34. doi: 10.1016/j.bmc.2006.04.026. Epub 2006 May 6. Bioorg Med Chem. 2006. PMID: 16682211 Free PMC article.

4

Construction of a small peptide library related to inhibitor OM99-2 and its structure-activity relationship to beta-secretase.

Hu B, Xiong B, Qiu BY, Li X, Yu HP, Xiao K, Wang X, Li J, Shen JK. Hu B, et al. Among authors: shen jk. Acta Pharmacol Sin. 2006 Dec;27(12):1586-93. doi: 10.1111/j.1745-7254.2006.00432.x. Acta Pharmacol Sin. 2006. PMID: 17112413

5

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.

Zhang L, Qiu B, Xiong B, Li X, Li J, Wang X, Li J, Shen J. Zhang L, et al. Among authors: shen j. Bioorg Med Chem Lett. 2007 Apr 15;17(8):2118-22. doi: 10.1016/j.bmcl.2007.01.094. Epub 2007 Feb 2. Bioorg Med Chem Lett. 2007. PMID: 17303416

6

Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.

Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J, Shen J. Ling Q, et al. Among authors: shen j. Bioorg Med Chem. 2008 Aug 1;16(15):7399-409. doi: 10.1016/j.bmc.2008.06.014. Epub 2008 Jun 13. Bioorg Med Chem. 2008. PMID: 18579388

7

DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks.

Xiong B, Liu K, Wu J, Burk DL, Jiang H, Shen J. Xiong B, et al. Among authors: shen j. Bioinformatics. 2008 Sep 15;24(18):2117-8. doi: 10.1093/bioinformatics/btn389. Epub 2008 Jul 25. Bioinformatics. 2008. PMID: 18658180

8

Discovery of potent beta-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids.

Zhu YP, Xiao K, Yu HP, Ma LP, Xiong B, Zhang HY, Wang X, Li JY, Li J, Shen JK. Zhu YP, et al. Among authors: shen jk. Acta Pharmacol Sin. 2009 Feb;30(2):259-69. doi: 10.1038/aps.2008.26. Epub 2009 Jan 26. Acta Pharmacol Sin. 2009. PMID: 19169270 Free PMC article.

9

MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.

Zhang Z, Meng T, He J, Li M, Tong LJ, Xiong B, Lin L, Shen J, Miao ZH, Ding J. Zhang Z, et al. Among authors: shen j. Invest New Drugs. 2010 Dec;28(6):715-28. doi: 10.1007/s10637-009-9303-z. Epub 2009 Aug 25. Invest New Drugs. 2010. PMID: 19705064

10

Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach.

Meng T, Wang J, Peng H, Fang G, Li M, Xiong B, Xie X, Zhang Y, Wang X, Shen J. Meng T, et al. Among authors: shen j. Eur J Med Chem. 2010 Mar;45(3):1133-9. doi: 10.1016/j.ejmech.2009.12.018. Epub 2009 Dec 16. Eur J Med Chem. 2010. PMID: 20047779

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