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Application of in situ diffraction in high-throughput structure determination platforms.
Aller P, Sanchez-Weatherby J, Foadi J, Winter G, Lobley CM, Axford D, Ashton AW, Bellini D, Brandao-Neto J, Culurgioni S, Douangamath A, Duman R, Evans G, Fisher S, Flaig R, Hall DR, Lukacik P, Mazzorana M, McAuley KE, Mykhaylyk V, Owen RL, Paterson NG, Romano P, Sandy J, Sorensen T, von Delft F, Wagner A, Warren A, Williams M, Stuart DI, Walsh MA. Aller P, et al. Among authors: warren a. Methods Mol Biol. 2015;1261:233-53. doi: 10.1007/978-1-4939-2230-7_13. Methods Mol Biol. 2015. PMID: 25502203 Review.
Visualization of membrane protein crystals in lipid cubic phase using X-ray imaging.
Warren AJ, Armour W, Axford D, Basham M, Connolley T, Hall DR, Horrell S, McAuley KE, Mykhaylyk V, Wagner A, Evans G. Warren AJ, et al. Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1252-9. doi: 10.1107/S0907444913011359. Epub 2013 Jun 15. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23793151 Free PMC article.
In vacuo X-ray data collection from graphene-wrapped protein crystals.
Warren AJ, Crawshaw AD, Trincao J, Aller P, Alcock S, Nistea I, Salgado PS, Evans G. Warren AJ, et al. Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2079-88. doi: 10.1107/S1399004715014194. Epub 2015 Sep 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26457431 Free PMC article.
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.
Brewitz L, Dumjahn L, Zhao Y, Owen CD, Laidlaw SM, Malla TR, Nguyen D, Lukacik P, Salah E, Crawshaw AD, Warren AJ, Trincao J, Strain-Damerell C, Carroll MW, Walsh MA, Schofield CJ. Brewitz L, et al. Among authors: warren aj. J Med Chem. 2023 Feb 23;66(4):2663-2680. doi: 10.1021/acs.jmedchem.2c01627. Epub 2023 Feb 9. J Med Chem. 2023. PMID: 36757959 Free PMC article.
VMXm - A sub-micron focus macromolecular crystallography beamline at Diamond Light Source.
Warren AJ, Trincao J, Crawshaw AD, Beale EV, Duller G, Stallwood A, Lunnon M, Littlewood R, Prescott A, Foster A, Smith N, Rehm G, Gayadeen S, Bloomer C, Alianelli L, Laundy D, Sutter J, Cahill L, Evans G. Warren AJ, et al. J Synchrotron Radiat. 2024 Nov 1;31(Pt 6):1593-1608. doi: 10.1107/S1600577524009160. Epub 2024 Oct 30. J Synchrotron Radiat. 2024. PMID: 39475835 Free PMC article.
1,580 results