Yang J - Search Results

1

Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors.

Zhao X, Xin M, Huang W, Ren Y, Jin Q, Tang F, Jiang H, Wang Y, Yang J, Mo S, Xiang H. Zhao X, et al. Among authors: yang j. Bioorg Med Chem. 2015 Jan 15;23(2):348-64. doi: 10.1016/j.bmc.2014.11.006. Epub 2014 Nov 10. Bioorg Med Chem. 2015. PMID: 25515957

2

Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors.

Ma J, Chen H, Yang J, Yu Z, Huang P, Yang H, Zheng B, Liu R, Li Q, Hu G, Chen Z. Ma J, et al. Among authors: yang h, yang j. Bioorg Med Chem. 2019 May 1;27(9):1871-1881. doi: 10.1016/j.bmc.2019.03.037. Epub 2019 Mar 22. Bioorg Med Chem. 2019. PMID: 30926312

3

Design, synthesis, biological evaluation, and structure-activity relationship (SAR) discussion of dipeptidyl boronate proteasome inhibitors, part I: comprehensive understanding of the SAR of alpha-amino acid boronates.

Zhu Y, Zhao X, Zhu X, Wu G, Li Y, Ma Y, Yuan Y, Yang J, Hu Y, Ai L, Gao Q. Zhu Y, et al. Among authors: yang j. J Med Chem. 2009 Jul 23;52(14):4192-9. doi: 10.1021/jm9005093. J Med Chem. 2009. PMID: 19537716

4

Synthesis, in vitro and in vivo biological evaluation, and comprehensive understanding of structure-activity relationships of dipeptidyl boronic acid proteasome inhibitors constructed from β-amino acids.

Zhu Y, Wu G, Zhu X, Ma Y, Zhao X, Li Y, Yuan Y, Yang J, Yu S, Shao F, Lei M. Zhu Y, et al. Among authors: yang j. J Med Chem. 2010 Dec 23;53(24):8619-26. doi: 10.1021/jm1009742. Epub 2010 Nov 15. J Med Chem. 2010. PMID: 21077681

5

N⁴-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo[2,3-d]pyrimidines as potent multiple receptor tyrosine kinase inhibitors: design, synthesis, and in vivo evaluation.

Gangjee A, Zaware N, Raghavan S, Yang J, Thorpe JE, Ihnat MA. Gangjee A, et al. Among authors: yang j. Bioorg Med Chem. 2012 Apr 1;20(7):2444-54. doi: 10.1016/j.bmc.2012.01.029. Epub 2012 Feb 4. Bioorg Med Chem. 2012. PMID: 22370340 Free PMC article.

6

Synthesis, in vitro and in vivo biological evaluation, docking studies, and structure--activity relationship (SAR) discussion of dipeptidyl boronic acid proteasome inhibitors composed of beta-amino acids.

Zhu Y, Zhu X, Wu G, Ma Y, Li Y, Zhao X, Yuan Y, Yang J, Yu S, Shao F, Li R, Ke Y, Lu A, Liu Z, Zhang L. Zhu Y, et al. Among authors: yang j. J Med Chem. 2010 Mar 11;53(5):1990-9. doi: 10.1021/jm901407s. J Med Chem. 2010. PMID: 20158184

7

Synthesis and biological evaluation of scopoletin derivatives.

Cai X, Yang J, Zhou J, Lu W, Hu C, Gu Z, Huo J, Wang X, Cao P. Cai X, et al. Among authors: yang j. Bioorg Med Chem. 2013 Jan 1;21(1):84-92. doi: 10.1016/j.bmc.2012.10.059. Epub 2012 Nov 15. Bioorg Med Chem. 2013. PMID: 23218780

8

Design, synthesis, and inhibition of platelet aggregation for some 1-o-chlorophenyl-1,2,3,4-tetrahydroisoquinoline derivatives.

Yang J, Hua WY, Wang FX, Wang ZY, Wang X. Yang J, et al. Bioorg Med Chem. 2004 Dec 15;12(24):6547-57. doi: 10.1016/j.bmc.2004.09.028. Bioorg Med Chem. 2004. PMID: 15556771

9

Antiangiogenic and antitumor agents. Design, synthesis, and evaluation of novel 2-amino-4-(3-bromoanilino)-6-benzylsubstituted pyrrolo[2,3-d]pyrimidines as inhibitors of receptor tyrosine kinases.

Gangjee A, Yang J, Ihnat MA, Kamat S. Gangjee A, et al. Among authors: yang j. Bioorg Med Chem. 2003 Nov 17;11(23):5155-70. doi: 10.1016/j.bmc.2003.08.034. Bioorg Med Chem. 2003. PMID: 14604679

10

Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.

Cao Z, Yang J, Xu R, Song Q, Zhang X, Liu H, Qiang X, Li Y, Tan Z, Deng Y. Cao Z, et al. Among authors: yang j. Bioorg Med Chem. 2018 Mar 1;26(5):1102-1115. doi: 10.1016/j.bmc.2018.01.030. Epub 2018 Feb 2. Bioorg Med Chem. 2018. PMID: 29409707

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