Zhang J - Search Results

1

Framework selection can influence pharmacokinetics of a humanized therapeutic antibody through differences in molecule charge.

Li B, Tesar D, Boswell CA, Cahaya HS, Wong A, Zhang J, Meng YG, Eigenbrot C, Pantua H, Diao J, Kapadia SB, Deng R, Kelley RF. Li B, et al. Among authors: zhang j. MAbs. 2014;6(5):1255-64. doi: 10.4161/mabs.29809. Epub 2014 Oct 30. MAbs. 2014. PMID: 25517310 Free PMC article.

2

Reproducible quantification of IgG uptake at endogenous and overexpressed FcRn levels at pH 7.4: Comparison of a wild type IgG and a stronger FcRn binding variant.

Zhang J, Vernes JM, Wen X, Oh E, Scales SJ, Meng YG. Zhang J, et al. J Immunol Methods. 2020 May;480:112767. doi: 10.1016/j.jim.2020.112767. Epub 2020 Feb 28. J Immunol Methods. 2020. PMID: 32119889

3

Real-time immuno-polymerase chain reaction in a 384-well format: detection of vascular endothelial growth factor and epidermal growth factor-like domain 7.

Zhang J, Vernes JM, Ni J, Nelson C, Wong A, Chen ST, Asundi A, Vandlen R, Meng YG. Zhang J, et al. Anal Biochem. 2014 Oct 15;463:61-6. doi: 10.1016/j.ab.2014.06.024. Epub 2014 Jul 8. Anal Biochem. 2014. PMID: 25013989

4

Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.

Gadkar K, Pastuskovas CV, Le Couter JE, Elliott JM, Zhang J, Lee CV, Sanowar S, Fuh G, Kim HS, Lombana TN, Spiess C, Nakamura M, Hass P, Shatz W, Meng YG, Scheer JM. Gadkar K, et al. Among authors: zhang j. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5390-400. doi: 10.1167/iovs.15-17108. Invest Ophthalmol Vis Sci. 2015. PMID: 26275136

5

An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy.

Chung AS, Wu X, Zhuang G, Ngu H, Kasman I, Zhang J, Vernes JM, Jiang Z, Meng YG, Peale FV, Ouyang W, Ferrara N. Chung AS, et al. Among authors: zhang j. Nat Med. 2013 Sep;19(9):1114-23. doi: 10.1038/nm.3291. Epub 2013 Aug 4. Nat Med. 2013. PMID: 23913124

6

Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema.

Agard NJ, Zhang G, Ridgeway J, Dicara DM, Chu PY, Ohri R, Sanowar S, Vernes JM, Chi H, Zhang J, Holz E, Paluch M, He G, Benson Y, Zhang J, Chan P, Tang N, Javale P, Wilson B, Barrett K, Rowntree RK, Hang J, Meng YG, Hass P, Fuh G, Piskol R, Bantseev V, Loyet KM, Tran JC, Wu C, Indjeian VB, Shivva V, Yan M. Agard NJ, et al. Among authors: zhang g, zhang j. Transl Vis Sci Technol. 2022 Oct 3;11(10):27. doi: 10.1167/tvst.11.10.27. Transl Vis Sci Technol. 2022. PMID: 36255358 Free PMC article.

7

Dramatic activation of an antibody by a single amino acid change in framework.

Liang WC, Yin J, Lupardus P, Zhang J, Loyet KM, Sudhamsu J, Wu Y. Liang WC, et al. Among authors: zhang j. Sci Rep. 2021 Nov 16;11(1):22365. doi: 10.1038/s41598-021-01530-w. Sci Rep. 2021. PMID: 34785671 Free PMC article.

8

EGFR over-expression and activation in high HER2, ER negative breast cancer cell line induces trastuzumab resistance.

Dua R, Zhang J, Nhonthachit P, Penuel E, Petropoulos C, Parry G. Dua R, et al. Among authors: zhang j. Breast Cancer Res Treat. 2010 Aug;122(3):685-97. doi: 10.1007/s10549-009-0592-x. Epub 2009 Oct 27. Breast Cancer Res Treat. 2010. PMID: 19859802

9

Detection of hepatocyte growth factor (HGF) ligand-c-MET receptor activation in formalin-fixed paraffin embedded specimens by a novel proximity assay.

Dua R, Zhang J, Parry G, Penuel E. Dua R, et al. Among authors: zhang j. PLoS One. 2011 Jan 21;6(1):e15932. doi: 10.1371/journal.pone.0015932. PLoS One. 2011. PMID: 21283737 Free PMC article.

10

Downregulation of Hedgehog signaling is required for organogenesis of the small intestine in Xenopus.

Zhang J, Rosenthal A, de Sauvage FJ, Shivdasani RA. Zhang J, et al. Dev Biol. 2001 Jan 1;229(1):188-202. doi: 10.1006/dbio.2000.9953. Dev Biol. 2001. PMID: 11133163 Free article.

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