Lane DP - Search Results

1

A unique role for p53 in the regulation of M2 macrophage polarization.

Li L, Ng DS, Mah WC, Almeida FF, Rahmat SA, Rao VK, Leow SC, Laudisi F, Peh MT, Goh AM, Lim JS, Wright GD, Mortellaro A, Taneja R, Ginhoux F, Lee CG, Moore PK, Lane DP. Li L, et al. Among authors: lane dp. Cell Death Differ. 2015 Jul;22(7):1081-93. doi: 10.1038/cdd.2014.212. Epub 2014 Dec 19. Cell Death Differ. 2015. PMID: 25526089 Free PMC article.

2

Regulation of the specific DNA binding function of p53.

Hupp TR, Meek DW, Midgley CA, Lane DP. Hupp TR, et al. Among authors: lane dp. Cell. 1992 Nov 27;71(5):875-86. doi: 10.1016/0092-8674(92)90562-q. Cell. 1992. PMID: 1423635

3

Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation.

Lu X, Park SH, Thompson TC, Lane DP. Lu X, et al. Among authors: lane dp. Cell. 1992 Jul 10;70(1):153-61. doi: 10.1016/0092-8674(92)90541-j. Cell. 1992. PMID: 1623518

4

R-Roscovitine simultaneously targets both the p53 and NF-kappaB pathways and causes potentiation of apoptosis: implications in cancer therapy.

Dey A, Wong ET, Cheok CF, Tergaonkar V, Lane DP. Dey A, et al. Among authors: lane dp. Cell Death Differ. 2008 Feb;15(2):263-73. doi: 10.1038/sj.cdd.4402257. Epub 2007 Nov 2. Cell Death Differ. 2008. PMID: 17975552

5

Specific activation of the p53 pathway by low dose actinomycin D: a new route to p53 based cyclotherapy.

Choong ML, Yang H, Lee MA, Lane DP. Choong ML, et al. Among authors: lane dp. Cell Cycle. 2009 Sep 1;8(17):2810-8. doi: 10.4161/cc.8.17.9503. Epub 2009 Sep 13. Cell Cycle. 2009. PMID: 19657224

6

Awakening guardian angels: drugging the p53 pathway.

Brown CJ, Lain S, Verma CS, Fersht AR, Lane DP. Brown CJ, et al. Among authors: lane dp. Nat Rev Cancer. 2009 Dec;9(12):862-73. doi: 10.1038/nrc2763. Nat Rev Cancer. 2009. PMID: 19935675 Review.

7

Mdm2 and p53 are highly conserved from placozoans to man.

Lane DP, Cheok CF, Brown C, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Cell Cycle. 2010 Feb 1;9(3):540-7. doi: 10.4161/cc.9.3.10516. Cell Cycle. 2010. PMID: 20081368

8

Differential binding of p53 and nutlin to MDM2 and MDMX: computational studies.

Joseph TL, Madhumalar A, Brown CJ, Lane DP, Verma CS. Joseph TL, et al. Among authors: lane dp. Cell Cycle. 2010 Mar 15;9(6):1167-81. doi: 10.4161/cc.9.6.11067. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20190571

9

Modulating the p53 pathway.

Dey A, Lane DP, Verma CS. Dey A, et al. Among authors: lane dp. Semin Cancer Biol. 2010 Feb;20(1):3-9. doi: 10.1016/j.semcancer.2010.02.004. Epub 2010 Mar 1. Semin Cancer Biol. 2010. PMID: 20193765 Review.

10

Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53.

Cheok CF, Kua N, Kaldis P, Lane DP. Cheok CF, et al. Among authors: lane dp. Cell Death Differ. 2010 Sep;17(9):1486-500. doi: 10.1038/cdd.2010.18. Epub 2010 Mar 5. Cell Death Differ. 2010. PMID: 20203688

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