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Long-term culture of genome-stable bipotent stem cells from adult human liver.
Huch M, Gehart H, van Boxtel R, Hamer K, Blokzijl F, Verstegen MM, Ellis E, van Wenum M, Fuchs SA, de Ligt J, van de Wetering M, Sasaki N, Boers SJ, Kemperman H, de Jonge J, Ijzermans JN, Nieuwenhuis EE, Hoekstra R, Strom S, Vries RR, van der Laan LJ, Cuppen E, Clevers H. Huch M, et al. Among authors: fuchs sa. Cell. 2015 Jan 15;160(1-2):299-312. doi: 10.1016/j.cell.2014.11.050. Epub 2014 Dec 18. Cell. 2015. PMID: 25533785 Free PMC article.
Large-Scale Production of LGR5-Positive Bipotential Human Liver Stem Cells.
Schneeberger K, Sánchez-Romero N, Ye S, van Steenbeek FG, Oosterhoff LA, Pla Palacin I, Chen C, van Wolferen ME, van Tienderen G, Lieshout R, Colemonts-Vroninks H, Schene I, Hoekstra R, Verstegen MMA, van der Laan LJW, Penning LC, Fuchs SA, Clevers H, De Kock J, Baptista PM, Spee B. Schneeberger K, et al. Among authors: fuchs sa. Hepatology. 2020 Jul;72(1):257-270. doi: 10.1002/hep.31037. Epub 2020 Apr 8. Hepatology. 2020. PMID: 31715015 Free PMC article.
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease.
Kruitwagen HS, Oosterhoff LA, van Wolferen ME, Chen C, Nantasanti Assawarachan S, Schneeberger K, Kummeling A, van Straten G, Akkerdaas IC, Vinke CR, van Steenbeek FG, van Bruggen LWL, Wolfswinkel J, Grinwis GCM, Fuchs SA, Gehart H, Geijsen N, Vries RG, Clevers H, Rothuizen J, Schotanus BA, Penning LC, Spee B. Kruitwagen HS, et al. Among authors: fuchs sa. Cells. 2020 Feb 11;9(2):410. doi: 10.3390/cells9020410. Cells. 2020. PMID: 32053895 Free PMC article.
Ethical challenges for pediatric liver organoid transplantation.
Schneemann SA, Boers SN, van Delden JJM, Nieuwenhuis EES, Fuchs SA, Bredenoord AL. Schneemann SA, et al. Among authors: fuchs sa. Sci Transl Med. 2020 Jul 15;12(552):eaau8471. doi: 10.1126/scitranslmed.aau8471. Sci Transl Med. 2020. PMID: 32669425 Review.
Prime editing for functional repair in patient-derived disease models.
Schene IF, Joore IP, Oka R, Mokry M, van Vugt AHM, van Boxtel R, van der Doef HPJ, van der Laan LJW, Verstegen MMA, van Hasselt PM, Nieuwenhuis EES, Fuchs SA. Schene IF, et al. Among authors: fuchs sa. Nat Commun. 2020 Oct 23;11(1):5352. doi: 10.1038/s41467-020-19136-7. Nat Commun. 2020. PMID: 33097693 Free PMC article.
Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct disease.
Verstegen MMA, Roos FJM, Burka K, Gehart H, Jager M, de Wolf M, Bijvelds MJC, de Jonge HR, Ardisasmita AI, van Huizen NA, Roest HP, de Jonge J, Koch M, Pampaloni F, Fuchs SA, Schene IF, Luider TM, van der Doef HPJ, Bodewes FAJA, de Kleine RHJ, Spee B, Kremers GJ, Clevers H, IJzermans JNM, Cuppen E, van der Laan LJW. Verstegen MMA, et al. Among authors: fuchs sa. Sci Rep. 2020 Dec 14;10(1):21900. doi: 10.1038/s41598-020-79082-8. Sci Rep. 2020. PMID: 33318612 Free PMC article.
The potential and limitations of intrahepatic cholangiocyte organoids to study inborn errors of metabolism.
Lehmann V, Schene IF, Ardisasmita AI, Liv N, Veenendaal T, Klumperman J, van der Doef HPJ, Verkade HJ, Verstegen MMA, van der Laan LJW, Jans JJM, Verhoeven-Duif NM, van Hasselt PM, Nieuwenhuis EES, Spee B, Fuchs SA. Lehmann V, et al. Among authors: fuchs sa. J Inherit Metab Dis. 2022 Mar;45(2):353-365. doi: 10.1002/jimd.12450. Epub 2021 Nov 3. J Inherit Metab Dis. 2022. PMID: 34671987 Free PMC article.
[Possible applications of organoids in medicine].
Mijnders M, Fuchs SA, Nieuwenhuis EES. Mijnders M, et al. Among authors: fuchs sa. Ned Tijdschr Geneeskd. 2022 Jan 12;166:D6011. Ned Tijdschr Geneeskd. 2022. PMID: 35138705 Dutch.
67 results