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Page 1
Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids.
Benchekroun M, Bartolini M, Egea J, Romero A, Soriano E, Pudlo M, Luzet V, Andrisano V, Jimeno ML, López MG, Wehle S, Gharbi T, Refouvelet B, de Andrés L, Herrera-Arozamena C, Monti B, Bolognesi ML, Rodríguez-Franco MI, Decker M, Marco-Contelles J, Ismaili L. Benchekroun M, et al. ChemMedChem. 2015 Mar;10(3):523-39. doi: 10.1002/cmdc.201402409. Epub 2014 Dec 23. ChemMedChem. 2015. PMID: 25537267
Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists.
Espadinha M, Dourado J, Lajarin-Cuesta R, Herrera-Arozamena C, Gonçalves LM, Rodríguez-Franco MI, de Los Rios C, Santos MM. Espadinha M, et al. Among authors: herrera arozamena c. ChemMedChem. 2017 Apr 6;12(7):537-545. doi: 10.1002/cmdc.201700037. Epub 2017 Mar 22. ChemMedChem. 2017. PMID: 28218498 Free article.
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada Valencia M, et al. Among authors: herrera arozamena c. Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30025348 Free article.
New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.
Estrada M, Herrera-Arozamena C, Pérez C, Viña D, Romero A, Morales-García JA, Pérez-Castillo A, Rodríguez-Franco MI. Estrada M, et al. Among authors: herrera arozamena c. Eur J Med Chem. 2016 Oct 4;121:376-386. doi: 10.1016/j.ejmech.2016.05.055. Epub 2016 May 25. Eur J Med Chem. 2016. PMID: 27267007 Free article.
New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties.
Estrada-Valencia M, Herrera-Arozamena C, Pérez C, Viña D, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada-Valencia M, et al. Among authors: herrera arozamena c. J Enzyme Inhib Med Chem. 2019 Dec;34(1):712-727. doi: 10.1080/14756366.2019.1581184. J Enzyme Inhib Med Chem. 2019. PMID: 31852270 Free PMC article.
Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades.
Herrera-Arozamena C, Estrada-Valencia M, López-Caballero P, Pérez C, Morales-García JA, Pérez-Castillo A, Sastre ED, Fernández-Mendívil C, Duarte P, Michalska P, Lombardía J, Senar S, León R, López MG, Rodríguez-Franco MI. Herrera-Arozamena C, et al. J Med Chem. 2022 Mar 24;65(6):4727-4751. doi: 10.1021/acs.jmedchem.1c01883. Epub 2022 Mar 4. J Med Chem. 2022. PMID: 35245051 Free PMC article.
Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential.
de la Fuente Revenga M, Fernández-Sáez N, Herrera-Arozamena C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Caignard DH, Rivara S, Rodríguez-Franco MI. de la Fuente Revenga M, et al. J Med Chem. 2015 Jun 25;58(12):4998-5014. doi: 10.1021/acs.jmedchem.5b00245. Epub 2015 Jun 10. J Med Chem. 2015. PMID: 26023814
13 results