Finzel BC - Search Results

1

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.

Park SW, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC, Schnappinger D, Aldrich CC. Park SW, et al. Among authors: finzel bc. Chem Biol. 2015 Jan 22;22(1):76-86. doi: 10.1016/j.chembiol.2014.11.012. Epub 2014 Dec 31. Chem Biol. 2015. PMID: 25556942 Free PMC article.

2

Mechanism-based inactivation by aromatization of the transaminase BioA involved in biotin biosynthesis in Mycobaterium tuberculosis.

Shi C, Geders TW, Park SW, Wilson DJ, Boshoff HI, Abayomi O, Barry CE 3rd, Schnappinger D, Finzel BC, Aldrich CC. Shi C, et al. Among authors: finzel bc. J Am Chem Soc. 2011 Nov 16;133(45):18194-201. doi: 10.1021/ja204036t. Epub 2011 Oct 24. J Am Chem Soc. 2011. PMID: 21988601 Free PMC article.

3

Bisubstrate adenylation inhibitors of biotin protein ligase from Mycobacterium tuberculosis.

Duckworth BP, Geders TW, Tiwari D, Boshoff HI, Sibbald PA, Barry CE 3rd, Schnappinger D, Finzel BC, Aldrich CC. Duckworth BP, et al. Among authors: finzel bc. Chem Biol. 2011 Nov 23;18(11):1432-41. doi: 10.1016/j.chembiol.2011.08.013. Chem Biol. 2011. PMID: 22118677 Free PMC article.

4

Inhibition of Mycobacterium tuberculosis transaminase BioA by aryl hydrazines and hydrazides.

Dai R, Wilson DJ, Geders TW, Aldrich CC, Finzel BC. Dai R, et al. Among authors: finzel bc. Chembiochem. 2014 Mar 3;15(4):575-86. doi: 10.1002/cbic.201300748. Epub 2014 Jan 31. Chembiochem. 2014. PMID: 24482078 Free PMC article.

5

Fragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.

Dai R, Geders TW, Liu F, Park SW, Schnappinger D, Aldrich CC, Finzel BC. Dai R, et al. Among authors: finzel bc. J Med Chem. 2015 Jul 9;58(13):5208-17. doi: 10.1021/acs.jmedchem.5b00092. Epub 2015 Jun 24. J Med Chem. 2015. PMID: 26068403 Free PMC article.

6

Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors.

Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M, Rhee KY, Schnappinger D, Finzel BC, Aldrich CC. Bockman MR, et al. Among authors: finzel bc. J Med Chem. 2015 Sep 24;58(18):7349-7369. doi: 10.1021/acs.jmedchem.5b00719. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26299766 Free PMC article.

7

Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.

Liu F, Dawadi S, Maize KM, Dai R, Park SW, Schnappinger D, Finzel BC, Aldrich CC. Liu F, et al. Among authors: finzel bc. J Med Chem. 2017 Jul 13;60(13):5507-5520. doi: 10.1021/acs.jmedchem.7b00189. Epub 2017 Jun 22. J Med Chem. 2017. PMID: 28594172 Free PMC article.

8

Rational Optimization of Mechanism-Based Inhibitors through Determination of the Microscopic Rate Constants of Inactivation.

Eiden CG, Maize KM, Finzel BC, Lipscomb JD, Aldrich CC. Eiden CG, et al. Among authors: finzel bc. J Am Chem Soc. 2017 May 31;139(21):7132-7135. doi: 10.1021/jacs.7b00962. Epub 2017 May 18. J Am Chem Soc. 2017. PMID: 28510452 Free PMC article.

9

Fragment-based identification of an inducible binding site on cell surface receptor CD44 for the design of protein-carbohydrate interaction inhibitors.

Liu LK, Finzel BC. Liu LK, et al. Among authors: finzel bc. J Med Chem. 2014 Mar 27;57(6):2714-25. doi: 10.1021/jm5000276. Epub 2014 Mar 7. J Med Chem. 2014. PMID: 24606063

10

Use of differential scanning fluorimetry to optimize the purification and crystallization of PLP-dependent enzymes.

Geders TW, Gustafson K, Finzel BC. Geders TW, et al. Among authors: finzel bc. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 May 1;68(Pt 5):596-600. doi: 10.1107/S1744309112012912. Epub 2012 Apr 21. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22691796 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

66 results

Search Page

Filters