Schreiber SL - Search Results

1

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.

Park SW, Casalena DE, Wilson DJ, Dai R, Nag PP, Liu F, Boyce JP, Bittker JA, Schreiber SL, Finzel BC, Schnappinger D, Aldrich CC. Park SW, et al. Among authors: schreiber sl. Chem Biol. 2015 Jan 22;22(1):76-86. doi: 10.1016/j.chembiol.2014.11.012. Epub 2014 Dec 31. Chem Biol. 2015. PMID: 25556942 Free PMC article.

2

A tricyclic ring system replaces the variable regions of peptides presented by three alleles of human MHC class I molecules.

Weiss GA, Collins EJ, Garboczi DN, Wiley DC, Schreiber SL. Weiss GA, et al. Among authors: schreiber sl. Chem Biol. 1995 Jun;2(6):401-7. doi: 10.1016/1074-5521(95)90221-x. Chem Biol. 1995. PMID: 9383442

3

Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis.

Haggarty SJ, Mayer TU, Miyamoto DT, Fathi R, King RW, Mitchison TJ, Schreiber SL. Haggarty SJ, et al. Among authors: schreiber sl. Chem Biol. 2000 Apr;7(4):275-86. doi: 10.1016/s1074-5521(00)00101-0. Chem Biol. 2000. PMID: 10780927

4

Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays.

Haggarty SJ, Koeller KM, Wong JC, Butcher RA, Schreiber SL. Haggarty SJ, et al. Among authors: schreiber sl. Chem Biol. 2003 May;10(5):383-96. doi: 10.1016/s1074-5521(03)00095-4. Chem Biol. 2003. PMID: 12770821

5

A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae.

Butcher RA, Schreiber SL. Butcher RA, et al. Among authors: schreiber sl. Chem Biol. 2003 Jun;10(6):521-31. doi: 10.1016/s1074-5521(03)00108-x. Chem Biol. 2003. PMID: 12837385

6

Identification of a small-molecule inhibitor of class Ia PI3Ks with cell-based screening.

Yang J, Shamji A, Matchacheep S, Schreiber SL. Yang J, et al. Among authors: schreiber sl. Chem Biol. 2007 Apr;14(4):371-7. doi: 10.1016/j.chembiol.2007.02.004. Chem Biol. 2007. PMID: 17462572

7

Small-molecule inducers of insulin expression in pancreatic alpha-cells.

Fomina-Yadlin D, Kubicek S, Walpita D, Dancik V, Hecksher-Sørensen J, Bittker JA, Sharifnia T, Shamji A, Clemons PA, Wagner BK, Schreiber SL. Fomina-Yadlin D, et al. Among authors: schreiber sl. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15099-104. doi: 10.1073/pnas.1010018107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696901 Free PMC article.

8

Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.

Youngsaye W, Vincent B, Hartland CL, Morgan BJ, Buhrlage SJ, Johnston S, Bittker JA, MacPherson L, Dandapani S, Palmer M, Whitesell L, Lindquist S, Schreiber SL, Munoz B. Youngsaye W, et al. Among authors: schreiber sl. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5502-5. doi: 10.1016/j.bmcl.2011.06.105. Epub 2011 Jun 30. Bioorg Med Chem Lett. 2011. PMID: 21802942 Free PMC article.

9

Identification of small-molecule inhibitors of Trypansoma cruzi replication.

Germain AR, Carmody LC, Dockendorff C, Galan-Rodriguez C, Rodriguez A, Johnston S, Bittker JA, MacPherson L, Dandapani S, Palmer M, Schreiber SL, Munoz B. Germain AR, et al. Among authors: schreiber sl. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7197-200. doi: 10.1016/j.bmcl.2011.09.057. Epub 2011 Sep 29. Bioorg Med Chem Lett. 2011. PMID: 22018462

10

Development of small-molecule probes that selectively kill cells induced to express mutant RAS.

Weïwer M, Bittker JA, Lewis TA, Shimada K, Yang WS, MacPherson L, Dandapani S, Palmer M, Stockwell BR, Schreiber SL, Munoz B. Weïwer M, et al. Among authors: schreiber sl. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1822-6. doi: 10.1016/j.bmcl.2011.09.047. Epub 2011 Sep 28. Bioorg Med Chem Lett. 2012. PMID: 22297109 Free PMC article.

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