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Page 1
Notch2 is required for inflammatory cytokine-driven goblet cell metaplasia in the lung.
Danahay H, Pessotti AD, Coote J, Montgomery BE, Xia D, Wilson A, Yang H, Wang Z, Bevan L, Thomas C, Petit S, London A, LeMotte P, Doelemeyer A, Vélez-Reyes GL, Bernasconi P, Fryer CJ, Edwards M, Capodieci P, Chen A, Hild M, Jaffe AB. Danahay H, et al. Among authors: bevan l. Cell Rep. 2015 Jan 13;10(2):239-52. doi: 10.1016/j.celrep.2014.12.017. Epub 2014 Dec 31. Cell Rep. 2015. PMID: 25558064 Free article.
ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK.
Munck JM, Berdini V, Bevan L, Brothwood JL, Castro J, Courtin A, East C, Ferraldeschi R, Heightman TD, Hindley CJ, Kucia-Tran J, Lyons JF, Martins V, Muench S, Murray CW, Norton D, O'Reilly M, Reader M, Rees DC, Rich SJ, Richardson CJ, Shah AD, Stanczuk L, Thompson NT, Wilsher NE, Woolford AJ, Wallis NG. Munck JM, et al. Among authors: bevan l. Mol Cancer Ther. 2021 Oct;20(10):1757-1768. doi: 10.1158/1535-7163.MCT-20-0909. Epub 2021 Jul 30. Mol Cancer Ther. 2021. PMID: 34330842
Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2.
Heightman TD, Berdini V, Bevan L, Buck IM, Carr MG, Courtin A, Coyle JE, Day JEH, East C, Fazal L, Griffiths-Jones CM, Howard S, Kucia-Tran J, Martins V, Muench S, Munck JM, Norton D, O'Reilly M, Palmer N, Pathuri P, Peakman TM, Reader M, Rees DC, Rich SJ, Shah A, Wallis NG, Walton H, Wilsher NE, Woolford AJ, Cooke M, Cousin D, Onions S, Shannon J, Watts J, Murray CW. Heightman TD, et al. Among authors: bevan l. J Med Chem. 2021 Aug 26;64(16):12286-12303. doi: 10.1021/acs.jmedchem.1c00905. Epub 2021 Aug 13. J Med Chem. 2021. PMID: 34387469
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
Chessari G, Hardcastle IR, Ahn JS, Anil B, Anscombe E, Bawn RH, Bevan LD, Blackburn TJ, Buck I, Cano C, Carbain B, Castro J, Cons B, Cully SJ, Endicott JA, Fazal L, Golding BT, Griffin RJ, Haggerty K, Harnor SJ, Hearn K, Hobson S, Holvey RS, Howard S, Jennings CE, Johnson CN, Lunec J, Miller DC, Newell DR, Noble MEM, Reeks J, Revill CH, Riedinger C, St Denis JD, Tamanini E, Thomas H, Thompson NT, Vinković M, Wedge SR, Williams PA, Wilsher NE, Zhang B, Zhao Y. Chessari G, et al. Among authors: bevan ld. J Med Chem. 2021 Apr 8;64(7):4071-4088. doi: 10.1021/acs.jmedchem.0c02188. Epub 2021 Mar 24. J Med Chem. 2021. PMID: 33761253
The COVID-19 Resource Centre: an invaluable tool for primary care.
Dabrowski A, Moore T, Bean T, Salach L, Hagel K, Bevan L, Scott-Meuser P, van Hal A, De Longhi C, Lang-Robertson K, Tulchinsky E. Dabrowski A, et al. Among authors: bevan l. J Can Health Libr Assoc. 2024 Aug 1;45(2):76-87. doi: 10.29173/jchla29742. eCollection 2024 Aug. J Can Health Libr Assoc. 2024. PMID: 39430652 Free PMC article.
Dissemination of the Women-Centred HIV Care Model: A Multimodal Process and Evaluation.
Koebel J, Kazemi M, Kennedy VL, Medeiros P, Bertozzi B, Bevan L, Tharao W, Logie CH, Underhill A, Pick N, King E, Kestler M, Yudin MH, Rana J, Carvalhal A, Webster K, Lee M, Islam S, Nicholson V, Ndung'u M, Narasimhan M, Gagnier B, Habanyama M, de Pokomandy A, Kaida A, Loutfy M; CHIWOS Research Team. Koebel J, et al. Among authors: bevan l. J Int Assoc Provid AIDS Care. 2024 Jan-Dec;23:23259582231226036. doi: 10.1177/23259582231226036. J Int Assoc Provid AIDS Care. 2024. PMID: 38389331 Free PMC article.
Surfacing the causal assumptions and active ingredients of healthcare quality improvement interventions: An application to primary care opioid prescribing.
McCleary N, Laur C, Presseau J, Dobell G, Lam JMC, Gushue S, Hagel K, Bevan L, Salach L, Desveaux L, M Ivers N. McCleary N, et al. Among authors: bevan l. Implement Res Pract. 2023 Nov 3;4:26334895231206569. doi: 10.1177/26334895231206569. eCollection 2023 Jan-Dec. Implement Res Pract. 2023. PMID: 37936967 Free PMC article.
67 results