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Expanding the paradigm of thiol redox in the thermophilic root of life.
Heinemann J, Hamerly T, Maaty WS, Movahed N, Steffens JD, Reeves BD, Hilmer JK, Therien J, Grieco PA, Peters JW, Bothner B. Heinemann J, et al. Among authors: bothner b. Biochim Biophys Acta. 2014 Jan;1840(1):80-5. doi: 10.1016/j.bbagen.2013.08.009. Epub 2013 Aug 17. Biochim Biophys Acta. 2014. PMID: 23962628
Unification of [FeFe]-hydrogenases into three structural and functional groups.
Poudel S, Tokmina-Lukaszewska M, Colman DR, Refai M, Schut GJ, King PW, Maness PC, Adams MW, Peters JW, Bothner B, Boyd ES. Poudel S, et al. Among authors: bothner b. Biochim Biophys Acta. 2016 Sep;1860(9):1910-21. doi: 10.1016/j.bbagen.2016.05.034. Epub 2016 May 27. Biochim Biophys Acta. 2016. PMID: 27241847
Mechanistic insights into energy conservation by flavin-based electron bifurcation.
Lubner CE, Jennings DP, Mulder DW, Schut GJ, Zadvornyy OA, Hoben JP, Tokmina-Lukaszewska M, Berry L, Nguyen DM, Lipscomb GL, Bothner B, Jones AK, Miller AF, King PW, Adams MWW, Peters JW. Lubner CE, et al. Among authors: bothner b. Nat Chem Biol. 2017 Jun;13(6):655-659. doi: 10.1038/nchembio.2348. Epub 2017 Apr 10. Nat Chem Biol. 2017. PMID: 28394885 Free PMC article.
The Electron Bifurcating FixABCX Protein Complex from Azotobacter vinelandii: Generation of Low-Potential Reducing Equivalents for Nitrogenase Catalysis.
Ledbetter RN, Garcia Costas AM, Lubner CE, Mulder DW, Tokmina-Lukaszewska M, Artz JH, Patterson A, Magnuson TS, Jay ZJ, Duan HD, Miller J, Plunkett MH, Hoben JP, Barney BM, Carlson RP, Miller AF, Bothner B, King PW, Peters JW, Seefeldt LC. Ledbetter RN, et al. Among authors: bothner b. Biochemistry. 2017 Aug 15;56(32):4177-4190. doi: 10.1021/acs.biochem.7b00389. Epub 2017 Aug 3. Biochemistry. 2017. PMID: 28704608 Free PMC article.
Two functionally distinct NADP+-dependent ferredoxin oxidoreductases maintain the primary redox balance of Pyrococcus furiosus.
Nguyen DMN, Schut GJ, Zadvornyy OA, Tokmina-Lukaszewska M, Poudel S, Lipscomb GL, Adams LA, Dinsmore JT, Nixon WJ, Boyd ES, Bothner B, Peters JW, Adams MWW. Nguyen DMN, et al. Among authors: bothner b. J Biol Chem. 2017 Sep 1;292(35):14603-14616. doi: 10.1074/jbc.M117.794172. Epub 2017 Jul 13. J Biol Chem. 2017. PMID: 28705933 Free PMC article.
H/D exchange mass spectrometry and statistical coupling analysis reveal a role for allostery in a ferredoxin-dependent bifurcating transhydrogenase catalytic cycle.
Berry L, Poudel S, Tokmina-Lukaszewska M, Colman DR, Nguyen DMN, Schut GJ, Adams MWW, Peters JW, Boyd ES, Bothner B. Berry L, et al. Among authors: bothner b. Biochim Biophys Acta Gen Subj. 2018 Jan;1862(1):9-17. doi: 10.1016/j.bbagen.2017.10.002. Epub 2017 Oct 6. Biochim Biophys Acta Gen Subj. 2018. PMID: 28993252
186 results