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Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing.
Limonciel A, Moenks K, Stanzel S, Truisi GL, Parmentier C, Aschauer L, Wilmes A, Richert L, Hewitt P, Mueller SO, Lukas A, Kopp-Schneider A, Leonard MO, Jennings P. Limonciel A, et al. Among authors: aschauer l. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18. doi: 10.1016/j.tiv.2014.12.011. Epub 2015 Jan 13. Toxicol In Vitro. 2015. PMID: 25596134
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics.
Wilmes A, Bielow C, Ranninger C, Bellwon P, Aschauer L, Limonciel A, Chassaigne H, Kristl T, Aiche S, Huber CG, Guillou C, Hewitt P, Leonard MO, Dekant W, Bois F, Jennings P. Wilmes A, et al. Among authors: aschauer l. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):117-27. doi: 10.1016/j.tiv.2014.10.006. Epub 2014 Oct 23. Toxicol In Vitro. 2015. PMID: 25450742
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model.
Jennings P, Weiland C, Limonciel A, Bloch KM, Radford R, Aschauer L, McMorrow T, Wilmes A, Pfaller W, Ahr HJ, Slattery C, Lock EA, Ryan MP, Ellinger-Ziegelbauer H. Jennings P, et al. Among authors: aschauer l. Arch Toxicol. 2012 Apr;86(4):571-89. doi: 10.1007/s00204-011-0780-4. Epub 2011 Nov 29. Arch Toxicol. 2012. PMID: 22124623
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.
Wilmes A, Limonciel A, Aschauer L, Moenks K, Bielow C, Leonard MO, Hamon J, Carpi D, Ruzek S, Handler A, Schmal O, Herrgen K, Bellwon P, Burek C, Truisi GL, Hewitt P, Di Consiglio E, Testai E, Blaauboer BJ, Guillou C, Huber CG, Lukas A, Pfaller W, Mueller SO, Bois FY, Dekant W, Jennings P. Wilmes A, et al. Among authors: aschauer l. J Proteomics. 2013 Feb 21;79:180-94. doi: 10.1016/j.jprot.2012.11.022. Epub 2012 Dec 10. J Proteomics. 2013. PMID: 23238060 Free article.
Delineation of the key aspects in the regulation of epithelial monolayer formation.
Aschauer L, Gruber LN, Pfaller W, Limonciel A, Athersuch TJ, Cavill R, Khan A, Gstraunthaler G, Grillari J, Grillari R, Hewitt P, Leonard MO, Wilmes A, Jennings P. Aschauer L, et al. Mol Cell Biol. 2013 Jul;33(13):2535-50. doi: 10.1128/MCB.01435-12. Epub 2013 Apr 22. Mol Cell Biol. 2013. PMID: 23608536 Free PMC article.
Interleukin-19 as a translational indicator of renal injury.
Jennings P, Crean D, Aschauer L, Limonciel A, Moenks K, Kern G, Hewitt P, Lhotta K, Lukas A, Wilmes A, Leonard MO. Jennings P, et al. Among authors: aschauer l. Arch Toxicol. 2015 Jan;89(1):101-6. doi: 10.1007/s00204-014-1237-3. Epub 2014 Apr 9. Arch Toxicol. 2015. PMID: 24714768
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