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159 results

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A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.
Kong B, Wu W, Cheng T, Schlitter AM, Qian C, Bruns P, Jian Z, Jäger C, Regel I, Raulefs S, Behler N, Irmler M, Beckers J, Friess H, Erkan M, Siveke JT, Tannapfel A, Hahn SA, Theis FJ, Esposito I, Kleeff J, Michalski CW. Kong B, et al. Among authors: bruns p. Gut. 2016 Apr;65(4):647-57. doi: 10.1136/gutjnl-2014-307616. Epub 2015 Jan 19. Gut. 2016. PMID: 25601637
Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW. Kong B, et al. Among authors: bruns p. Gut. 2018 Jan;67(1):146-156. doi: 10.1136/gutjnl-2015-310913. Epub 2016 Sep 19. Gut. 2018. PMID: 27646934
Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma.
Jian Z, Cheng T, Zhang Z, Raulefs S, Shi K, Steiger K, Maeritz N, Kleigrewe K, Hofmann T, Benitz S, Bruns P, Lamp D, Jastroch M, Akkan J, Jäger C, Huang P, Nie S, Shen S, Zou X, Ceyhan GO, Michalski CW, Friess H, Kleeff J, Kong B. Jian Z, et al. Among authors: bruns p. Cell Mol Gastroenterol Hepatol. 2018 Jul 26;6(4):429-449. doi: 10.1016/j.jcmgh.2018.07.003. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30258965 Free PMC article.
Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.
Benitz S, Straub T, Mahajan UM, Mutter J, Czemmel S, Unruh T, Wingerath B, Deubler S, Fahr L, Cheng T, Nahnsen S, Bruns P, Kong B, Raulefs S, Ceyhan GO, Mayerle J, Steiger K, Esposito I, Kleeff J, Michalski CW, Regel I. Benitz S, et al. Among authors: bruns p. Gut. 2019 Nov;68(11):2007-2018. doi: 10.1136/gutjnl-2018-317208. Epub 2019 Apr 6. Gut. 2019. PMID: 30954952
Metabolism gene signatures and surgical site infections in abdominal surgery.
Kong B, Bruns P, Raulefs S, Rieder S, Paul L, Prazeresda Costa O, Buch T, Theis FJ, Michalski CW, Kleeff J. Kong B, et al. Among authors: bruns p. Int J Surg. 2015 Feb;14:67-74. doi: 10.1016/j.ijsu.2015.01.009. Epub 2015 Jan 16. Int J Surg. 2015. PMID: 25599917 Free article.
Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer.
Müller S, Raulefs S, Bruns P, Afonso-Grunz F, Plötner A, Thermann R, Jäger C, Schlitter AM, Kong B, Regel I, Roth WK, Rotter B, Hoffmeier K, Kahl G, Koch I, Theis FJ, Kleeff J, Winter P, Michalski CW. Müller S, et al. Among authors: bruns p. Mol Cancer. 2015 Apr 25;14:94. doi: 10.1186/s12943-015-0358-5. Mol Cancer. 2015. PMID: 25910082 Free PMC article.
Erratum to: Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer.
Müller S, Raulefs S, Bruns P, Afonso-Grunz F, Plötner A, Thermann R, Jäger C, Schlitter AM, Kong B, Regel I, Roth WK, Rotter B, Hoffmeier K, Kahl G, Koch I, Theis FJ, Kleeff J, Winter P, Michalski CW. Müller S, et al. Among authors: bruns p. Mol Cancer. 2015 Jul 31;14:144. doi: 10.1186/s12943-015-0401-6. Mol Cancer. 2015. PMID: 26227492 Free PMC article. No abstract available.
A novel NHE1-centered signaling cassette drives epidermal growth factor receptor-dependent pancreatic tumor metastasis and is a target for combination therapy.
Cardone RA, Greco MR, Zeeberg K, Zaccagnino A, Saccomano M, Bellizzi A, Bruns P, Menga M, Pilarsky C, Schwab A, Alves F, Kalthoff H, Casavola V, Reshkin SJ. Cardone RA, et al. Among authors: bruns p. Neoplasia. 2015 Feb;17(2):155-66. doi: 10.1016/j.neo.2014.12.003. Neoplasia. 2015. PMID: 25748234 Free PMC article.
159 results