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A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.
Kong B, Wu W, Cheng T, Schlitter AM, Qian C, Bruns P, Jian Z, Jäger C, Regel I, Raulefs S, Behler N, Irmler M, Beckers J, Friess H, Erkan M, Siveke JT, Tannapfel A, Hahn SA, Theis FJ, Esposito I, Kleeff J, Michalski CW. Kong B, et al. Among authors: cheng t. Gut. 2016 Apr;65(4):647-57. doi: 10.1136/gutjnl-2014-307616. Epub 2015 Jan 19. Gut. 2016. PMID: 25601637
Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma.
Jian Z, Cheng T, Zhang Z, Raulefs S, Shi K, Steiger K, Maeritz N, Kleigrewe K, Hofmann T, Benitz S, Bruns P, Lamp D, Jastroch M, Akkan J, Jäger C, Huang P, Nie S, Shen S, Zou X, Ceyhan GO, Michalski CW, Friess H, Kleeff J, Kong B. Jian Z, et al. Among authors: cheng t. Cell Mol Gastroenterol Hepatol. 2018 Jul 26;6(4):429-449. doi: 10.1016/j.jcmgh.2018.07.003. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30258965 Free PMC article.
Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.
Benitz S, Straub T, Mahajan UM, Mutter J, Czemmel S, Unruh T, Wingerath B, Deubler S, Fahr L, Cheng T, Nahnsen S, Bruns P, Kong B, Raulefs S, Ceyhan GO, Mayerle J, Steiger K, Esposito I, Kleeff J, Michalski CW, Regel I. Benitz S, et al. Among authors: cheng t. Gut. 2019 Nov;68(11):2007-2018. doi: 10.1136/gutjnl-2018-317208. Epub 2019 Apr 6. Gut. 2019. PMID: 30954952
7,590 results