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Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance.
Ketscher L, Hannß R, Morales DJ, Basters A, Guerra S, Goldmann T, Hausmann A, Prinz M, Naumann R, Pekosz A, Utermöhlen O, Lenschow DJ, Knobeloch KP. Ketscher L, et al. Among authors: lenschow dj. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1577-82. doi: 10.1073/pnas.1412881112. Epub 2015 Jan 20. Proc Natl Acad Sci U S A. 2015. PMID: 25605921 Free PMC article.
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Giannakopoulos NV, Luo JK, Papov V, Zou W, Lenschow DJ, Jacobs BS, Borden EC, Li J, Virgin HW, Zhang DE. Giannakopoulos NV, et al. Among authors: lenschow dj. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506. doi: 10.1016/j.bbrc.2005.08.132. Biochem Biophys Res Commun. 2005. PMID: 16139798
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.
Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW 4th. Lenschow DJ, et al. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1371-6. doi: 10.1073/pnas.0607038104. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227866 Free PMC article.
Antiviral Properties of ISG15.
Lenschow DJ. Lenschow DJ. Viruses. 2010 Oct;2(10):2154-2168. doi: 10.3390/v2102154. Epub 2010 Sep 28. Viruses. 2010. PMID: 21994614 Free PMC article.
Emerging roles for immunomodulatory functions of free ISG15.
Campbell JA, Lenschow DJ. Campbell JA, et al. Among authors: lenschow dj. J Interferon Cytokine Res. 2013 Dec;33(12):728-38. doi: 10.1089/jir.2013.0064. Epub 2013 Sep 6. J Interferon Cytokine Res. 2013. PMID: 24010825 Free PMC article. Review.
The antiviral activities of ISG15.
Morales DJ, Lenschow DJ. Morales DJ, et al. Among authors: lenschow dj. J Mol Biol. 2013 Dec 13;425(24):4995-5008. doi: 10.1016/j.jmb.2013.09.041. Epub 2013 Oct 3. J Mol Biol. 2013. PMID: 24095857 Free PMC article. Review.
69 results