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Page 1
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.
Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E. Johnson MR, et al. Among authors: rossetti t. Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031. Nat Commun. 2015. PMID: 25615886 Free PMC article.
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease.
Johnson MR, Shkura K, Langley SR, Delahaye-Duriez A, Srivastava P, Hill WD, Rackham OJ, Davies G, Harris SE, Moreno-Moral A, Rotival M, Speed D, Petrovski S, Katz A, Hayward C, Porteous DJ, Smith BH, Padmanabhan S, Hocking LJ, Starr JM, Liewald DC, Visconti A, Falchi M, Bottolo L, Rossetti T, Danis B, Mazzuferi M, Foerch P, Grote A, Helmstaedter C, Becker AJ, Kaminski RM, Deary IJ, Petretto E. Johnson MR, et al. Among authors: rossetti t. Nat Neurosci. 2016 Feb;19(2):223-32. doi: 10.1038/nn.4205. Epub 2015 Dec 21. Nat Neurosci. 2016. PMID: 26691832 Free article.
Implication of sestrin3 in epilepsy and its comorbidities.
Lovisari F, Roncon P, Soukoupova M, Paolone G, Labasque M, Ingusci S, Falcicchia C, Marino P, Johnson M, Rossetti T, Petretto E, Leclercq K, Kaminski RM, Moyon B, Webster Z, Simonato M, Zucchini S. Lovisari F, et al. Among authors: rossetti t. Brain Commun. 2020 Oct 9;3(1):fcaa130. doi: 10.1093/braincomms/fcaa130. eCollection 2021. Brain Commun. 2020. PMID: 33758823 Free PMC article.
Addition to "Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation".
Sun S, Fushimi M, Rossetti T, Kaur N, Ferreira J, Miller M, Quast J, van den Heuvel J, Steegborn C, Levin LR, Buck J, Myers RW, Kargman S, Liverton N, Meinke PT, Huggins DJ. Sun S, et al. Among authors: rossetti t. J Chem Inf Model. 2024 Feb 12;64(3):1106. doi: 10.1021/acs.jcim.4c00068. Epub 2024 Jan 23. J Chem Inf Model. 2024. PMID: 38258980 No abstract available.
Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation.
Sun S, Fushimi M, Rossetti T, Kaur N, Ferreira J, Miller M, Quast J, van den Heuvel J, Steegborn C, Levin LR, Buck J, Myers RW, Kargman S, Liverton N, Meinke PT, Huggins DJ. Sun S, et al. Among authors: rossetti t. J Chem Inf Model. 2023 May 8;63(9):2828-2841. doi: 10.1021/acs.jcim.2c01577. Epub 2023 Apr 15. J Chem Inf Model. 2023. PMID: 37060320
On-demand male contraception via acute inhibition of soluble adenylyl cyclase.
Balbach M, Rossetti T, Ferreira J, Ghanem L, Ritagliati C, Myers RW, Huggins DJ, Steegborn C, Miranda IC, Meinke PT, Buck J, Levin LR. Balbach M, et al. Among authors: rossetti t. Nat Commun. 2023 Feb 14;14(1):637. doi: 10.1038/s41467-023-36119-6. Nat Commun. 2023. PMID: 36788210 Free PMC article.
Short-term CaMKII inhibition with tatCN19o does not erase pre-formed memory and is neuroprotective in non-rodents.
Rumian NL, Brown CN, Hendry-Hofer TB, Rossetti T, Orfila JE, Tullis JE, Dwoskin LP, Buonarati OR, Lisman JE, Quillinan N, Herson PS, Bebarta VS, Bayer KU. Rumian NL, et al. Among authors: rossetti t. bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.523316. doi: 10.1101/2023.01.23.523316. bioRxiv. 2023. Update in: J Biol Chem. 2023 May;299(5):104693. doi: 10.1016/j.jbc.2023.104693 PMID: 36747773 Free PMC article. Updated. Preprint.
35 results