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VacA generates a protective intracellular reservoir for Helicobacter pylori that is eliminated by activation of the lysosomal calcium channel TRPML1.
Capurro MI, Greenfield LK, Prashar A, Xia S, Abdullah M, Wong H, Zhong XZ, Bertaux-Skeirik N, Chakrabarti J, Siddiqui I, O'Brien C, Dong X, Robinson L, Peek RM Jr, Philpott DJ, Zavros Y, Helmrath M, Jones NL. Capurro MI, et al. Nat Microbiol. 2019 Aug;4(8):1411-1423. doi: 10.1038/s41564-019-0441-6. Epub 2019 May 20. Nat Microbiol. 2019. PMID: 31110360 Free PMC article.
478 results