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PE859, a novel tau aggregation inhibitor, reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo.
Okuda M, Hijikuro I, Fujita Y, Wu X, Nakayama S, Sakata Y, Noguchi Y, Ogo M, Akasofu S, Ito Y, Soeda Y, Tsuchiya N, Tanaka N, Takahashi T, Sugimoto H. Okuda M, et al. Among authors: hijikuro i. PLoS One. 2015 Feb 6;10(2):e0117511. doi: 10.1371/journal.pone.0117511. eCollection 2015. PLoS One. 2015. PMID: 25659102 Free PMC article.
Design, synthesis, evaluation and QSAR analysis of N(1)-substituted norcymserine derivatives as selective butyrylcholinesterase inhibitors.
Takahashi J, Hijikuro I, Kihara T, Murugesh MG, Fuse S, Kunimoto R, Tsumura Y, Akaike A, Niidome T, Okuno Y, Takahashi T, Sugimoto H. Takahashi J, et al. Among authors: hijikuro i. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1718-20. doi: 10.1016/j.bmcl.2010.01.057. Epub 2010 Jan 20. Bioorg Med Chem Lett. 2010. PMID: 20137934
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