Wexler D - Search Results

1

Effect of hepatic or renal impairment on the pharmacokinetics of canagliflozin, a sodium glucose co-transporter 2 inhibitor.

Devineni D, Curtin CR, Marbury TC, Smith W, Vaccaro N, Wexler D, Vandebosch A, Rusch S, Stieltjes H, Wajs E. Devineni D, et al. Among authors: wexler d. Clin Ther. 2015 Mar 1;37(3):610-628.e4. doi: 10.1016/j.clinthera.2014.12.013. Epub 2015 Feb 3. Clin Ther. 2015. PMID: 25659911

2

Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects.

Sha S, Devineni D, Ghosh A, Polidori D, Chien S, Wexler D, Shalayda K, Demarest K, Rothenberg P. Sha S, et al. Among authors: wexler d. Diabetes Obes Metab. 2011 Jul;13(7):669-72. doi: 10.1111/j.1463-1326.2011.01406.x. Diabetes Obes Metab. 2011. PMID: 21457428 Clinical Trial.

3

A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe.

Ezzet F, Krishna G, Wexler DB, Statkevich P, Kosoglou T, Batra VK. Ezzet F, et al. Among authors: wexler db. Clin Ther. 2001 Jun;23(6):871-85. doi: 10.1016/s0149-2918(01)80075-8. Clin Ther. 2001. PMID: 11440287 Clinical Trial.

4

A brief survey of first-in-human studies.

Wexler D, Bertelsen KM. Wexler D, et al. J Clin Pharmacol. 2011 Jul;51(7):988-93. doi: 10.1177/0091270010377631. Epub 2010 Jul 29. J Clin Pharmacol. 2011. PMID: 20671293

5

The plasma concentration and LDL-C relationship in patients receiving ezetimibe.

Ezzet F, Wexler D, Statkevich P, Kosoglou T, Patrick J, Lipka L, Mellars L, Veltri E, Batra V. Ezzet F, et al. Among authors: wexler d. J Clin Pharmacol. 2001 Sep;41(9):943-9. doi: 10.1177/00912700122010915. J Clin Pharmacol. 2001. PMID: 11549098 Clinical Trial.

6

Oral bioavailability of posaconazole in fasted healthy subjects: comparison between three regimens and basis for clinical dosage recommendations.

Ezzet F, Wexler D, Courtney R, Krishna G, Lim J, Laughlin M. Ezzet F, et al. Among authors: wexler d. Clin Pharmacokinet. 2005;44(2):211-20. doi: 10.2165/00003088-200544020-00006. Clin Pharmacokinet. 2005. PMID: 15656699 Clinical Trial.

7

Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection.

Ullmann AJ, Cornely OA, Burchardt A, Hachem R, Kontoyiannis DP, Töpelt K, Courtney R, Wexler D, Krishna G, Martinho M, Corcoran G, Raad I. Ullmann AJ, et al. Among authors: wexler d. Antimicrob Agents Chemother. 2006 Feb;50(2):658-66. doi: 10.1128/AAC.50.2.658-666.2006. Antimicrob Agents Chemother. 2006. PMID: 16436724 Free PMC article. Clinical Trial.

8

Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults.

Courtney R, Wexler D, Radwanski E, Lim J, Laughlin M. Courtney R, et al. Among authors: wexler d. Br J Clin Pharmacol. 2004 Feb;57(2):218-22. doi: 10.1046/j.1365-2125.2003.01977.x. Br J Clin Pharmacol. 2004. PMID: 14748822 Free PMC article. Clinical Trial.

9

Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers.

Sansone-Parsons A, Krishna G, Calzetta A, Wexler D, Kantesaria B, Rosenberg MA, Saltzman MA. Sansone-Parsons A, et al. Among authors: wexler d. Antimicrob Agents Chemother. 2006 May;50(5):1881-3. doi: 10.1128/AAC.50.5.1881-1883.2006. Antimicrob Agents Chemother. 2006. PMID: 16641468 Free PMC article. Clinical Trial.

10

Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study.

Wexler D, Courtney R, Richards W, Banfield C, Lim J, Laughlin M. Wexler D, et al. Eur J Pharm Sci. 2004 Apr;21(5):645-53. doi: 10.1016/j.ejps.2004.01.005. Eur J Pharm Sci. 2004. PMID: 15066665 Clinical Trial.

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