Jasper JR - Search Results

1

The small-molecule fast skeletal troponin activator, CK-2127107, improves exercise tolerance in a rat model of heart failure.

Hwee DT, Kennedy AR, Hartman JJ, Ryans J, Durham N, Malik FI, Jasper JR. Hwee DT, et al. Among authors: jasper jr. J Pharmacol Exp Ther. 2015 Apr;353(1):159-68. doi: 10.1124/jpet.114.222224. Epub 2015 Feb 12. J Pharmacol Exp Ther. 2015. PMID: 25678535

2

Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model.

Hwee DT, Kennedy A, Ryans J, Russell AJ, Jia Z, Hinken AC, Morgans DJ, Malik FI, Jasper JR. Hwee DT, et al. Among authors: jasper jr. PLoS One. 2014 May 7;9(5):e96921. doi: 10.1371/journal.pone.0096921. eCollection 2014. PLoS One. 2014. PMID: 24805850 Free PMC article.

3

The Ca²⁺ sensitizer CK-2066260 increases myofibrillar Ca²⁺ sensitivity and submaximal force selectively in fast skeletal muscle.

Hwee DT, Cheng AJ, Hartman JJ, Hinken AC, Lee K, Durham N, Russell AJ, Malik FI, Westerblad H, Jasper JR. Hwee DT, et al. Among authors: jasper jr. J Physiol. 2017 Mar 1;595(5):1657-1670. doi: 10.1113/JP273248. Epub 2017 Jan 24. J Physiol. 2017. PMID: 27869319 Free PMC article.

4

Fast skeletal muscle troponin activator CK-2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction.

Cheng AJ, Hwee DT, Kim LH, Durham N, Yang HT, Hinken AC, Kennedy AR, Terjung RL, Jasper JR, Malik FI, Westerblad H. Cheng AJ, et al. Among authors: jasper jr. J Physiol. 2019 Sep;597(17):4615-4625. doi: 10.1113/JP278235. Epub 2019 Jul 17. J Physiol. 2019. PMID: 31246276 Free PMC article.

5

Reduced force of diaphragm muscle fibers in patients with chronic thromboembolic pulmonary hypertension.

Manders E, Bonta PI, Kloek JJ, Symersky P, Bogaard HJ, Hooijman PE, Jasper JR, Malik FI, Stienen GJ, Vonk-Noordegraaf A, de Man FS, Ottenheijm CA. Manders E, et al. Among authors: jasper jr. Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L20-8. doi: 10.1152/ajplung.00113.2016. Epub 2016 May 17. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27190061 Free PMC article.

6

More roles for the (passive) giant. Focus on "The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms".

Hwee DT, Jasper JR. Hwee DT, et al. Among authors: jasper jr. Am J Physiol Cell Physiol. 2016 Jan 1;310(1):C17-8. doi: 10.1152/ajpcell.00310.2015. Epub 2015 Nov 4. Am J Physiol Cell Physiol. 2016. PMID: 26538091 Free PMC article. No abstract available.

7

Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency.

Lee EJ, De Winter JM, Buck D, Jasper JR, Malik FI, Labeit S, Ottenheijm CA, Granzier H. Lee EJ, et al. Among authors: jasper jr. PLoS One. 2013;8(2):e55861. doi: 10.1371/journal.pone.0055861. Epub 2013 Feb 20. PLoS One. 2013. PMID: 23437068 Free PMC article.

8

Fast skeletal muscle troponin activator in the dy2J muscular dystrophy model.

Miciak JJ, Warsing LC, Tibbs ME, Jasper JR, Jampel SB, Malik FI, Tankersley C, Wagner KR. Miciak JJ, et al. Among authors: jasper jr. Muscle Nerve. 2013 Aug;48(2):279-85. doi: 10.1002/mus.23848. Epub 2013 Jun 29. Muscle Nerve. 2013. PMID: 23512724

9

Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations.

de Winter JM, Buck D, Hidalgo C, Jasper JR, Malik FI, Clarke NF, Stienen GJ, Lawlor MW, Beggs AH, Ottenheijm CA, Granzier H. de Winter JM, et al. Among authors: jasper jr. J Med Genet. 2013 Jun;50(6):383-92. doi: 10.1136/jmedgenet-2012-101470. Epub 2013 Apr 9. J Med Genet. 2013. PMID: 23572184 Free PMC article.

10

Diaphragm fiber strength is reduced in critically ill patients and restored by a troponin activator.

Hooijman PE, Beishuizen A, de Waard MC, de Man FS, Vermeijden JW, Steenvoorde P, Bouwman RA, Lommen W, van Hees HW, Heunks LM, Dickhoff C, van der Peet DL, Girbes AR, Jasper JR, Malik FI, Stienen GJ, Hartemink KJ, Paul MA, Ottenheijm CA. Hooijman PE, et al. Among authors: jasper jr. Am J Respir Crit Care Med. 2014 Apr 1;189(7):863-5. doi: 10.1164/rccm.201312-2260LE. Am J Respir Crit Care Med. 2014. PMID: 24684359 Free PMC article. No abstract available.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

60 results

Search Page

Filters