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Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of irinotecan and its main metabolites in human plasma and its application in a clinical pharmacokinetic study.
Marangon E, Posocco B, Mazzega E, Toffoli G. Marangon E, et al. Among authors: toffoli g. PLoS One. 2015 Feb 17;10(2):e0118194. doi: 10.1371/journal.pone.0118194. eCollection 2015. PLoS One. 2015. PMID: 25689738 Free PMC article.
Pharmacogenetics of irinotecan.
Toffoli G, Cecchin E, Corona G, Boiocchi M. Toffoli G, et al. Curr Med Chem Anticancer Agents. 2003 May;3(3):225-37. doi: 10.2174/1568011033482477. Curr Med Chem Anticancer Agents. 2003. PMID: 12769780 Review.
The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer.
Toffoli G, Cecchin E, Corona G, Russo A, Buonadonna A, D'Andrea M, Pasetto LM, Pessa S, Errante D, De Pangher V, Giusto M, Medici M, Gaion F, Sandri P, Galligioni E, Bonura S, Boccalon M, Biason P, Frustaci S. Toffoli G, et al. J Clin Oncol. 2006 Jul 1;24(19):3061-8. doi: 10.1200/JCO.2005.05.5400. J Clin Oncol. 2006. PMID: 16809730 Clinical Trial.
Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer.
Toffoli G, Cecchin E, Gasparini G, D'Andrea M, Azzarello G, Basso U, Mini E, Pessa S, De Mattia E, Lo Re G, Buonadonna A, Nobili S, De Paoli P, Innocenti F. Toffoli G, et al. J Clin Oncol. 2010 Feb 10;28(5):866-71. doi: 10.1200/JCO.2009.23.6125. Epub 2009 Dec 28. J Clin Oncol. 2010. PMID: 20038727 Free PMC article. Clinical Trial.
349 results