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RASA3 is a critical inhibitor of RAP1-dependent platelet activation.
Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W. Stefanini L, et al. Among authors: mackman n. J Clin Invest. 2015 Apr;125(4):1419-32. doi: 10.1172/JCI77993. Epub 2015 Feb 23. J Clin Invest. 2015. PMID: 25705885 Free PMC article.
Platelet ITAM signaling is critical for vascular integrity in inflammation.
Boulaftali Y, Hess PR, Getz TM, Cholka A, Stolla M, Mackman N, Owens AP 3rd, Ware J, Kahn ML, Bergmeier W. Boulaftali Y, et al. Among authors: mackman n. J Clin Invest. 2013 Feb;123(2):908-16. doi: 10.1172/JCI65154. Epub 2013 Jan 25. J Clin Invest. 2013. PMID: 23348738 Free PMC article.
CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice.
Boulaftali Y, Owens AP 3rd, Beale A, Piatt R, Casari C, Lee RH, Conley PB, Paul DS, Mackman N, Bergmeier W. Boulaftali Y, et al. Among authors: mackman n. Arterioscler Thromb Vasc Biol. 2016 May;36(5):792-9. doi: 10.1161/ATVBAHA.115.306347. Epub 2016 Mar 17. Arterioscler Thromb Vasc Biol. 2016. PMID: 26988592 Free PMC article.
Platelet Signaling Pathways and New Inhibitors.
Grover SP, Bergmeier W, Mackman N. Grover SP, et al. Among authors: mackman n. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):e28-e35. doi: 10.1161/ATVBAHA.118.310224. Arterioscler Thromb Vasc Biol. 2018. PMID: 29563117 Free PMC article. Review. No abstract available.
Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm.
Owens AP 3rd, Edwards TL, Antoniak S, Geddings JE, Jahangir E, Wei WQ, Denny JC, Boulaftali Y, Bergmeier W, Daugherty A, Sampson UKA, Mackman N. Owens AP 3rd, et al. Among authors: mackman n. Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):2032-2041. doi: 10.1161/ATVBAHA.115.305537. Epub 2015 Jul 2. Arterioscler Thromb Vasc Biol. 2015. PMID: 26139462 Free PMC article.
527 results