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Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.
Chen L, Sung SS, Yip ML, Lawrence HR, Ren Y, Guida WC, Sebti SM, Lawrence NJ, Wu J. Chen L, et al. Among authors: wu j. Mol Pharmacol. 2006 Aug;70(2):562-70. doi: 10.1124/mol.106.025536. Epub 2006 May 22. Mol Pharmacol. 2006. PMID: 16717135
Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112.
Chen L, Pernazza D, Scott LM, Lawrence HR, Ren Y, Luo Y, Wu X, Sung SS, Guida WC, Sebti SM, Lawrence NJ, Wu J. Chen L, et al. Among authors: wu x, wu j. Biochem Pharmacol. 2010 Sep 15;80(6):801-10. doi: 10.1016/j.bcp.2010.05.019. Epub 2010 May 25. Biochem Pharmacol. 2010. PMID: 20510203 Free PMC article.
Enhanced anti-melanoma efficacy of interferon alfa-2b via inhibition of Shp2.
Win-Piazza H, Schneeberger VE, Chen L, Pernazza D, Lawrence HR, Sebti SM, Lawrence NJ, Wu J. Win-Piazza H, et al. Among authors: wu j. Cancer Lett. 2012 Jul 1;320(1):81-5. doi: 10.1016/j.canlet.2012.01.034. Epub 2012 Feb 1. Cancer Lett. 2012. PMID: 22306001 Free PMC article.
SHP2E76K mutant promotes lung tumorigenesis in transgenic mice.
Schneeberger VE, Luetteke N, Ren Y, Berns H, Chen L, Foroutan P, Martinez GV, Haura EB, Chen J, Coppola D, Wu J. Schneeberger VE, et al. Among authors: wu j. Carcinogenesis. 2014 Aug;35(8):1717-25. doi: 10.1093/carcin/bgu025. Epub 2014 Jan 30. Carcinogenesis. 2014. PMID: 24480804 Free PMC article.
Preclinical Modeling of KIF5B-RET Fusion Lung Adenocarcinoma.
Huang Q, Schneeberger VE, Luetteke N, Jin C, Afzal R, Budzevich MM, Makanji RJ, Martinez GV, Shen T, Zhao L, Fung KM, Haura EB, Coppola D, Wu J. Huang Q, et al. Among authors: wu j. Mol Cancer Ther. 2016 Oct;15(10):2521-2529. doi: 10.1158/1535-7163.MCT-16-0258. Epub 2016 Aug 5. Mol Cancer Ther. 2016. PMID: 27496134 Free PMC article.
77,171 results
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