Pinheiro J - Search Results

1

Causal inference methods to assess safety upper bounds in randomized trials with noncompliance.

Wang Y, Berlin JA, Pinheiro J, Wilcox MA. Wang Y, et al. Among authors: pinheiro j. Clin Trials. 2015 Jun;12(3):265-75. doi: 10.1177/1740774515572352. Epub 2015 Mar 1. Clin Trials. 2015. PMID: 25733675 Free PMC article.

2

Designing multiregional trials under the discrete random effects model.

Lan KK, Pinheiro J, Chen F. Lan KK, et al. Among authors: pinheiro j. J Biopharm Stat. 2014;24(2):415-28. doi: 10.1080/10543406.2013.860155. J Biopharm Stat. 2014. PMID: 24605977

3

University of Pennsylvania 8th annual conference on statistical issues in clinical trials: Pragmatic clinical trials (morning panel).

Dodd LE, Lantos JD, Pinheiro J. Dodd LE, et al. Among authors: pinheiro j. Clin Trials. 2016 Oct;13(5):493-503. doi: 10.1177/1740774516657547. Epub 2016 Jul 17. Clin Trials. 2016. PMID: 27430711 No abstract available.

4

Model-based dose finding under model uncertainty using general parametric models.

Pinheiro J, Bornkamp B, Glimm E, Bretz F. Pinheiro J, et al. Stat Med. 2014 May 10;33(10):1646-61. doi: 10.1002/sim.6052. Epub 2013 Dec 3. Stat Med. 2014. PMID: 24302486

5

Model-based clinical drug development in the past, present and future: a commentary.

Kimko H, Pinheiro J. Kimko H, et al. Among authors: pinheiro j. Br J Clin Pharmacol. 2015 Jan;79(1):108-16. doi: 10.1111/bcp.12341. Br J Clin Pharmacol. 2015. PMID: 24527997 Free PMC article. Review.

6

A novel quantification of information for longitudinal data analyzed by mixed-effects modeling.

Yuan M, Li Y, Yang Y, Xu J, Tao F, Zhao L, Zhou H, Pinheiro J, Xu XS. Yuan M, et al. Among authors: pinheiro j. Pharm Stat. 2020 Jul;19(4):388-398. doi: 10.1002/pst.1996. Epub 2020 Jan 27. Pharm Stat. 2020. PMID: 31989784

7

Further Evaluation of Covariate Analysis using Empirical Bayes Estimates in Population Pharmacokinetics: the Perception of Shrinkage and Likelihood Ratio Test.

Xu XS, Yuan M, Yang H, Feng Y, Xu J, Pinheiro J. Xu XS, et al. Among authors: pinheiro j. AAPS J. 2017 Jan;19(1):264-273. doi: 10.1208/s12248-016-0001-4. Epub 2016 Oct 19. AAPS J. 2017. PMID: 27761720

8

Full covariate modelling approach in population pharmacokinetics: understanding the underlying hypothesis tests and implications of multiplicity.

Xu XS, Yuan M, Zhu H, Yang Y, Wang H, Zhou H, Xu J, Zhang L, Pinheiro J. Xu XS, et al. Among authors: pinheiro j. Br J Clin Pharmacol. 2018 Jul;84(7):1525-1534. doi: 10.1111/bcp.13577. Epub 2018 May 3. Br J Clin Pharmacol. 2018. PMID: 29522646 Free PMC article.

9

Estimating significance level and power comparisons for testing multiple endpoints in clinical trials.

Gong J, Pinheiro JC, DeMets DL. Gong J, et al. Among authors: pinheiro jc. Control Clin Trials. 2000 Aug;21(4):313-29. doi: 10.1016/s0197-2456(00)00049-0. Control Clin Trials. 2000. PMID: 10913807

10

Efficient algorithms for covariate analysis with dynamic data using nonlinear mixed-effects model.

Yuan M, Zhu Z, Yang Y, Zhao M, Sasser K, Hamadeh H, Pinheiro J, Xu XS. Yuan M, et al. Among authors: pinheiro j. Stat Methods Med Res. 2021 Jan;30(1):233-243. doi: 10.1177/0962280220949898. Epub 2020 Aug 24. Stat Methods Med Res. 2021. PMID: 32838650

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