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Estimation of the binding modes with important human cytochrome P450 enzymes, drug interaction potential, pharmacokinetics, and hepatotoxicity of ginger components using molecular docking, computational, and pharmacokinetic modeling studies.
Qiu JX, Zhou ZW, He ZX, Zhang X, Zhou SF, Zhu S. Qiu JX, et al. Among authors: he zx. Drug Des Devel Ther. 2015 Feb 16;9:841-66. doi: 10.2147/DDDT.S74669. eCollection 2015. Drug Des Devel Ther. 2015. PMID: 25733806 Free PMC article.
MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1).
Li M, Yang Y, He ZX, Zhou ZW, Yang T, Guo P, Zhang X, Zhou SF. Li M, et al. Among authors: he zx. Drug Metab Dispos. 2014 Jan;42(1):44-61. doi: 10.1124/dmd.113.052670. Epub 2013 Oct 8. Drug Metab Dispos. 2014. PMID: 24104199
Xyloketal B, a marine compound, acts on a network of molecular proteins and regulates the activity and expression of rat cytochrome P450 3a: a bioinformatic and animal study.
Su J, Chang C, Xiang Q, Zhou ZW, Luo R, Yang L, He ZX, Yang H, Li J, Bei Y, Xu J, Zhang M, Zhang Q, Su Z, Huang Y, Pang J, Zhou SF. Su J, et al. Among authors: he zx. Drug Des Devel Ther. 2014 Dec 12;8:2555-602. doi: 10.2147/DDDT.S73476. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25548518 Free PMC article.
Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells.
Zhang LF, Zhou ZW, Wang ZH, Du YH, He ZX, Cao C, Zhou SF. Zhang LF, et al. Among authors: he zx. Drug Des Devel Ther. 2014 Dec 24;9:241-72. doi: 10.2147/DDDT.S71106. eCollection 2015. Drug Des Devel Ther. 2014. Retraction in: Drug Des Devel Ther. 2022 Nov 21;16:4041-4042. doi: 10.2147/DDDT.S397859 PMID: 25565776 Free PMC article. Retracted.
430 results