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Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense.
Jantsch J, Schatz V, Friedrich D, Schröder A, Kopp C, Siegert I, Maronna A, Wendelborn D, Linz P, Binger KJ, Gebhardt M, Heinig M, Neubert P, Fischer F, Teufel S, David JP, Neufert C, Cavallaro A, Rakova N, Küper C, Beck FX, Neuhofer W, Muller DN, Schuler G, Uder M, Bogdan C, Luft FC, Titze J. Jantsch J, et al. Among authors: binger kj. Cell Metab. 2015 Mar 3;21(3):493-501. doi: 10.1016/j.cmet.2015.02.003. Cell Metab. 2015. PMID: 25738463 Free PMC article.
Elementary immunology: Na+ as a regulator of immunity.
Schatz V, Neubert P, Schröder A, Binger K, Gebhard M, Müller DN, Luft FC, Titze J, Jantsch J. Schatz V, et al. Pediatr Nephrol. 2017 Feb;32(2):201-210. doi: 10.1007/s00467-016-3349-x. Epub 2016 Feb 26. Pediatr Nephrol. 2017. PMID: 26921211 Free PMC article. Review.
Macrophages in homeostatic immune function.
Jantsch J, Binger KJ, Müller DN, Titze J. Jantsch J, et al. Among authors: binger kj. Front Physiol. 2014 May 5;5:146. doi: 10.3389/fphys.2014.00146. eCollection 2014. Front Physiol. 2014. PMID: 24847274 Free PMC article. Review.
HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting.
Neubert P, Weichselbaum A, Reitinger C, Schatz V, Schröder A, Ferdinand JR, Simon M, Bär AL, Brochhausen C, Gerlach RG, Tomiuk S, Hammer K, Wagner S, van Zandbergen G, Binger KJ, Müller DN, Kitada K, Clatworthy MR, Kurts C, Titze J, Abdullah Z, Jantsch J. Neubert P, et al. Among authors: binger kj. Autophagy. 2019 Nov;15(11):1899-1916. doi: 10.1080/15548627.2019.1596483. Epub 2019 Apr 14. Autophagy. 2019. PMID: 30982460 Free PMC article.
NCX1 represents an ionic Na+ sensing mechanism in macrophages.
Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. Neubert P, et al. Among authors: binger kj. PLoS Biol. 2020 Jun 22;18(6):e3000722. doi: 10.1371/journal.pbio.3000722. eCollection 2020 Jun. PLoS Biol. 2020. PMID: 32569301 Free PMC article.
Autophagy and the (Pro)renin Receptor.
Binger KJ, Muller DN. Binger KJ, et al. Front Endocrinol (Lausanne). 2013 Oct 21;4:155. doi: 10.3389/fendo.2013.00155. Front Endocrinol (Lausanne). 2013. PMID: 24155743 Free PMC article. Review.
Sodium chloride, SGK1, and Th17 activation.
Binger KJ, Linker RA, Muller DN, Kleinewietfeld M. Binger KJ, et al. Pflugers Arch. 2015 Mar;467(3):543-50. doi: 10.1007/s00424-014-1659-z. Epub 2014 Dec 4. Pflugers Arch. 2015. PMID: 25471348 Review.
High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Binger KJ, Gebhardt M, Heinig M, Rintisch C, Schroeder A, Neuhofer W, Hilgers K, Manzel A, Schwartz C, Kleinewietfeld M, Voelkl J, Schatz V, Linker RA, Lang F, Voehringer D, Wright MD, Hubner N, Dechend R, Jantsch J, Titze J, Müller DN. Binger KJ, et al. J Clin Invest. 2015 Nov 2;125(11):4223-38. doi: 10.1172/JCI80919. Epub 2015 Oct 20. J Clin Invest. 2015. PMID: 26485286 Free PMC article.
Salt Transiently Inhibits Mitochondrial Energetics in Mononuclear Phagocytes.
Geisberger S, Bartolomaeus H, Neubert P, Willebrand R, Zasada C, Bartolomaeus T, McParland V, Swinnen D, Geuzens A, Maifeld A, Krampert L, Vogl M, Mähler A, Wilck N, Markó L, Tilic E, Forslund SK, Binger KJ, Stegbauer J, Dechend R, Kleinewietfeld M, Jantsch J, Kempa S, Müller DN. Geisberger S, et al. Among authors: binger kj. Circulation. 2021 Jul 13;144(2):144-158. doi: 10.1161/CIRCULATIONAHA.120.052788. Epub 2021 Apr 28. Circulation. 2021. PMID: 33906377 Free PMC article.
45 results