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Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs.
Hosseini M, Jiang L, Sørensen HP, Jensen JK, Christensen A, Fogh S, Yuan C, Andersen LM, Huang M, Andreasen PA, Jensen KJ. Hosseini M, et al. Among authors: sorensen hp. Mol Pharmacol. 2011 Oct;80(4):585-97. doi: 10.1124/mol.111.072280. Epub 2011 Jun 30. Mol Pharmacol. 2011. PMID: 21719463
The binding mechanism of a peptidic cyclic serine protease inhibitor.
Jiang L, Svane AS, Sørensen HP, Jensen JK, Hosseini M, Chen Z, Weydert C, Nielsen JT, Christensen A, Yuan C, Jensen KJ, Nielsen NC, Malmendal A, Huang M, Andreasen PA. Jiang L, et al. Among authors: sorensen hp. J Mol Biol. 2011 Sep 16;412(2):235-50. doi: 10.1016/j.jmb.2011.07.028. Epub 2011 Jul 23. J Mol Biol. 2011. PMID: 21802428
A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility.
Zhao B, Xu P, Jiang L, Paaske B, Kromann-Hansen T, Jensen JK, Sørensen HP, Liu Z, Nielsen JT, Christensen A, Hosseini M, Sørensen KK, Nielsen NC, Jensen KJ, Huang M, Andreasen PA. Zhao B, et al. Among authors: sorensen hp. PLoS One. 2014 Dec 29;9(12):e115872. doi: 10.1371/journal.pone.0115872. eCollection 2014. PLoS One. 2014. PMID: 25545505 Free PMC article.
Catalytic properties of ADAM12 and its domain deletion mutants.
Jacobsen J, Visse R, Sørensen HP, Enghild JJ, Brew K, Wewer UM, Nagase H. Jacobsen J, et al. Among authors: sorensen hp. Biochemistry. 2008 Jan 15;47(2):537-47. doi: 10.1021/bi701629c. Epub 2007 Dec 15. Biochemistry. 2008. PMID: 18081311
25 results