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Page 1
T cell gene-engineering to enhance GVT and suppress GVHD.
Ghorashian S, Nicholson E, Stauss HJ. Ghorashian S, et al. Best Pract Res Clin Haematol. 2011 Sep;24(3):421-33. doi: 10.1016/j.beha.2011.05.004. Epub 2011 Jun 28. Best Pract Res Clin Haematol. 2011. PMID: 21925095 Review.
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells.
Qasim W, Zhan H, Samarasinghe S, Adams S, Amrolia P, Stafford S, Butler K, Rivat C, Wright G, Somana K, Ghorashian S, Pinner D, Ahsan G, Gilmour K, Lucchini G, Inglott S, Mifsud W, Chiesa R, Peggs KS, Chan L, Farzeneh F, Thrasher AJ, Vora A, Pule M, Veys P. Qasim W, et al. Among authors: ghorashian s. Sci Transl Med. 2017 Jan 25;9(374):eaaj2013. doi: 10.1126/scitranslmed.aaj2013. Sci Transl Med. 2017. PMID: 28123068
Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia.
Rossig C, Pule M, Altvater B, Saiagh S, Wright G, Ghorashian S, Clifton-Hadley L, Champion K, Sattar Z, Popova B, Hackshaw A, Smith P, Roberts T, Biagi E, Dreno B, Rousseau R, Kailayangiri S, Ahlmann M, Hough R, Kremens B, Sauer MG, Veys P, Goulden N, Cummins M, Amrolia PJ. Rossig C, et al. Among authors: ghorashian s. Leukemia. 2017 May;31(5):1087-1095. doi: 10.1038/leu.2017.39. Epub 2017 Jan 27. Leukemia. 2017. PMID: 28126984 Free article. Clinical Trial.
Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR.
Ghorashian S, Kramer AM, Onuoha S, Wright G, Bartram J, Richardson R, Albon SJ, Casanovas-Company J, Castro F, Popova B, Villanueva K, Yeung J, Vetharoy W, Guvenel A, Wawrzyniecka PA, Mekkaoui L, Cheung GW, Pinner D, Chu J, Lucchini G, Silva J, Ciocarlie O, Lazareva A, Inglott S, Gilmour KC, Ahsan G, Ferrari M, Manzoor S, Champion K, Brooks T, Lopes A, Hackshaw A, Farzaneh F, Chiesa R, Rao K, Bonney D, Samarasinghe S, Goulden N, Vora A, Veys P, Hough R, Wynn R, Pule MA, Amrolia PJ. Ghorashian S, et al. Nat Med. 2019 Sep;25(9):1408-1414. doi: 10.1038/s41591-019-0549-5. Epub 2019 Sep 2. Nat Med. 2019. PMID: 31477906 Clinical Trial.
The role of immunotherapy in relapse/refractory precursor-B acute lymphoblastic leukaemia: real-life UK/Ireland experience in children and young adults.
Ottaviano G, Baird S, Bonney D, Connor P, Cummins M, Evans P, Gibson B, Hough R, Ingham D, Kelly A, Qureshi A, Lancaster D, Moppett J, Norton A, Payne J, Stockley S, Ghorashian S, Amrolia P, Qasim W, Vora A. Ottaviano G, et al. Among authors: ghorashian s. Br J Haematol. 2021 Jan;192(2):e42-e44. doi: 10.1111/bjh.17198. Epub 2020 Nov 20. Br J Haematol. 2021. PMID: 33216967 Free article. No abstract available.
Graft-versus-host disease induced by tisagenlecleucel in patients after allogeneic stem cell transplantation.
Gabelli M, Marks DI, Sharplin K, Lazareva A, Mullanfiroze K, Farish S, Burridge S, Velangi M, Rampling D, Mozayani B, Chiesa R, Lucchini G, Samarasinghe S, Bartram J, Ghorashian S. Gabelli M, et al. Among authors: ghorashian s. Br J Haematol. 2021 Dec;195(5):805-811. doi: 10.1111/bjh.17737. Epub 2021 Jul 28. Br J Haematol. 2021. PMID: 34322864 No abstract available.
51 results